The development of new strategies to attenuate exercise-induced muscle damage may be helpful for training regimens. The aim of this study was to determine whether a oral formulation of angiotensin Ang-(1-7)[HPβCD/Ang-(1-7)] is effective to reduce pain, and muscle damage markers after eccentric-overload exercise. HPβCD (Placebo) and HPβCD/Ang-(1-7) (Ang-(1-7) group were treated for 7 days (one capsule/day). The pain was measured by visual analogue scale, maximal strength (MS) using force platform...

The current study aimed to determine the effects of sildenafil-associated aerobic exercise training (ET) on the physical performance, hemodynamic, autonomic and inflammatory parameters of rats. Male Wistar rats were randomly assigned to: sedentary rats placebo-treated (SP); sedentary rats sildenafil-treated (SS); trained rats placebo-treated (TP); and trained rats sildenafil-treated (TS). Sildenafil treatment consisted of 8 weeks of daily oral gavage (1.5 mg/kg), one hour before the session of E...

Functional threshold power is defined as the highest power output a cyclist can maintain in a quasi-steady state for approximately 60 min (FTP₆₀). In order to improve practicality for regular evaluations, FTP₆₀could theoretically be determined as 95% of the mean power output in a 20-min time trial (FTP₂₀). This study tested this assumption and the validity of FTP₂₀and FTP₆₀against the individual anaerobic threshold (IAT). Twenty-three trained male cyclists performed an incremental test to exhaus...

During upper-body tasks, use of the lower body is important for minimizing physiological strain and maximizing performance. The lower body has an integral role duringstandingupper-body tasks, however, it is less clear if it is also important duringseatedupper-body tasks. We determined the extent to which the lower body influenced seated arm cranking performance. Eleven males performed incremental (40+20 W·3 min⁻¹) and short-duration maximal effort (5 s, 120 rpm) arm cranking trials with and with...