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DOI 10.1055/s-00000031

Klinische Monatsblätter für Augenheilkunde

In dieser Ausgabe:

Grundlagen der praktischen Kontaktlinsenanpassung. Teil 2

In Zeiten der unbegrenzten Verfügbarkeit der Austauschlinsen im Internet und beim Discounter ist die Kontaktlinse mehr und mehr zum Lifestyle-, aber auch zum Wegwerfprodukt geworden. Dieser zweite Teil des Beitrags thematisiert die praktische Durchführung einer Kontaktlinsenanpassung und geht auf mögliche Komplikationen ein, die beim Kontaktlinsentragen auftreten können.

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Gelsolin-Amyloidosis – An Exceptional Cause of Blepharochalasis

AGelhereditary gelsolin amyloidosisBCblepharochalasisG-Aguanine-to-adeninekDakilodaltons 

The term amyloidosis comprises a group of diseases with different triggers, but which all ultimately lead to the deposition of abnormally folded and aggregated proteins in tissues, so-called amyloid fibrils. In cases of autosomal dominantly inherited gelsolin amyloidosis (AGel, MIM#105120), a single base mutation in gelsolin causes a progressive chronic disease with various systemic symptoms. The typical dia...

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The Lucerne Protocol for the Production of Autologous Serum Eyedrops

Background There are a variety of protocols for manufacturing autologous serum (AS) eye drops. The Lucerne protocol for the production of AS eye drops uses a slightly reduced gravitational (g)-force and time for the centrifugation process (2500 × g for 10 minutes), compared to previously published optimised protocols, to obtain high levels of epitheliotropic growth factors (3000 × g for 15 minutes). The goal of this study was to compare the concentrations of growth factors, albumin and lysozyme i...

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The Spectrum of Maculopathy in Mitochondrial DNA A3243G Mutation: A Case Series of Six Patients

Background The mitochondrial DNA (mtDNA) A3243G point mutation encompasses a heterogenous group of disorders including mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), maternally inherited diabetes and deafness (MIDD), and, rarely, chronic progressive external ophthalmoplegia (CPEO). Regardless of the clinical phenotype, a specific retinopathy has been associated with the presence of this mitochondrial DNA mutation. We present six female patients exhibiting retinop...

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The Efficacy of Ab Externo Canaloplasty by Using a Nonabsorbable Suture and No Viscoelastics; IOP Results, Intraoperative and Early Complication Rates within 6-Month Follow-Up Period

Background To report the efficacy of ab externo canaloplasty by exclusively using only a nonabsorbable suture as a standalone operation or combined with phacoemulsification in terms of mean intraocular pressure (IOP), medication reduction, and intra- and postoperative complication rates as well as additional glaucoma surgery.

Patients and Methods Forty-eight patients with primary open-angle glaucoma (POAG) and 50 eyes were divided into two groups according to the operation performed (Group A canalo...

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Surgical Outcomes of Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in Patients with Open-Angle Glaucoma – A Retrospective Case Series

Purpose To evaluate the outcome of gonioscopy-assisted transluminal trabeculotomy (GATT) in patients with open-angle glaucoma (OAG).

Participants and Methods A retrospective case series of patients with uncontrolled OAG treated by GATT at the cantonal Hospital Lucerne, a tertiary referral center, between October 2018 and July 2019 with a minimal 6-month follow-up period. Main outcome measures were intraocular pressure (IOP), number of antiglaucoma medications, and complications.

Results Thirty-one ey...

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Visual Outcomes after Anti-VEGF Therapy for Exudative Age-Related Macular Degeneration in a Real-Life Setting

Background To report visual outcomes of anti-vascular endothelial growth factor (anti-VEGF) therapy for exudative age-related macular degeneration (AMD) in a real-life setting.

Patients and Methods Retrospective case series of consecutive patients treated with either ranibizumab and/or aflibercept for monolateral or bilateral exudative AMD. A physician established the indication for treatment and administered the injections. An independent physician confirmed the indication for primary treatment. A...

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