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Die Zeitschrift Klinische Pädiatrie erscheint 7-mal jährlich und veröffentlicht Beiträge aus dem Gebiet der (klinischen) Pädiatrie und deren Grenzgebiete in deutscher und englischer Sprache. Die Zeitschrift wird in allen wichtigen internationalen Zitationsdiensten geführt.  

DOI 10.1055/s-00000034

Klinische Pädiatrie

In dieser Ausgabe:

Aktualisierte AWMF Leitlinie über die Diagnostik und Therapie der akuten lymphoblastische Leukämie im Kindesalter

Die Überlebensraten der akuten lymphoblastischen Leukämie (ALL) im Kindesalter erreichen heutzutage in Abhängigkeit von den initialen Risikofaktoren im Durchschnitt 85% . Die erfolgreiche Behandlung dieser schweren Erkrankung beruht auf der Entwicklung mul-timodaler Therapiekonzepte, auf der Basis einer sich stetig verbesserten molekulargeneti-schen Characterisierung der Erkrankung mit der Identifizierung neuer Risikofaktoren. Die Diagnostik des Therapieansprechens und die daraus resultierende S...

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Current German Guidelines on Diagnosis and Treatment of Secondary Hemochromatosis in Patients with Congenital Anemias

Adequate diagnosis and treatment of secondary hemochromatosis in patients with congenital anemias is important for reducing long-term mortality and morbidity as for improving patients' quality of life. Due to the strong migration movements during recent years, the number of patients in Germany suffering from hemoglobinopathies as some of the most relevant disorders in the context of iron overload (IOL) has increased enormously. Many of these patients had received inadequate medical care in their...

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Coping with Diffuse Intrinsic Pontine Glioma in Children – Findings from an Interview Study on Bereaved Parents

Background Diffuse midline glioma (DMG) is the most common malignant glioma in early childhood with median survival of only eleven months. This retrospective interview study investigates specific coping strategies and needs of affected parents.

Patients 13 interviews with parents of seven children who died from DMG at the age of five to 16 years were conducted in 2016.

Method The used method is a problem-oriented guided interview with consecutive content and evaluating structuring analysis according ...

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Is There a Role for Laboratory Parameters in Predicting Coronary Artery Involvement in Kawasaki Disease?

Background Kawasaki disease (KD) may cause cardiac and coronary complications. Since definite markers to accurately predict coronary involvement is not present, we aimed to analyze the role of hematological indices [neutrophil-to lymphocyte ratio (NLR), platelet-to lymphocyte ratio (PLR), lymphocyte-to monocyte ratio (LMR), and mean platelet volume (MPV)-to lymphocyte ratio (MPVLR)], prognostic nutritional index (PNI) and systemic immune-inflammation index (SII) in predicting coronary involvement...

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Haploidentical Hematopoietic Stem Cell Transplantation in a 3-Year-Old Girl with Congenital Amegakaryocytic Thrombocytopenia: A Case Report

Congenital amegakaryocytic thrombocytopenia (CAMT) is an autosomal recessive disorder characterized by severe thrombocytopenia that presents soon after birth and is usually not accompanied by specific somatic malformations [Germeshausen M, Ballmaier M. Best Pract Res Clin Haematol 2021; 34: 101286]. CAMT is more prevalent in females than males [Ballmaier M, Germeshausen M. Semin Thromb Hemost 2011; 37: 673–681; Germeshausen M, Ballmaier M. Haematologica 2021; 106: 2439–2448], in contrast to othe...

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DIPG- Very Long-Term Survivors – are There Factors Which May Predict a Better Outcome?

Diffuse intrinsic pontine gliomas (DIPG) account for 15–20% of all central nervous system tumors in children, and are the main cause of death in children with brain tumors [Hargrave DR et al., J Neurooncol 2006; 77: 267 f]. Although stereotactic biopsies seem to regain acceptance, due to neurosurgical techniques, the diagnosis of DIPG is currently still based on characteristic MRI findings (tumor centered in the pons associated with an expansion of more than 50%, dark on T1-weighted images, brig...

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Buchtipps Pädiatrie

Differenzialdiagnosen in der Kinder- und Jugendmedizin
Robert PloierDifferenzialdiagnosen in der Kinder- und Jugendmedizin

EUR [D] 52,99Inkl. gesetzl. MwSt.

Praktische Pneumologie in der Pädiatrie - Diagnostik
Matthias Griese, Thomas Nicolai, Robert Dalla, Christoph Döhlemann, Richard dePraktische Pneumologie in der Pädiatrie - Diagnostik

Rationale Differenzialdiagnostik

EUR [D] 29,99Inkl. gesetzl. MwSt.

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