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Die Zeitschrift Klinische Pädiatrie erscheint 7-mal jährlich und veröffentlicht Beiträge aus dem Gebiet der (klinischen) Pädiatrie und deren Grenzgebiete in deutscher und englischer Sprache. Die Zeitschrift wird in allen wichtigen internationalen Zitationsdiensten geführt.  

DOI 10.1055/s-00000034

Klinische Pädiatrie

In dieser Ausgabe:

Evaluation of Peripheral Lymphadenopathies in Children in a Single Center: Predictive Factors for Malignancy

Background Lymphadenopathy (LAP) is a common finding in pediatric patients. It was aimed to determine predictive factors in distinguishing cases with malignant or benign lymphadenopathy in this study.

Subjects and methods Between January 2022 and January 2023, 101 patients (1-16 years old) with lymphadenopathy were retrospectively examined.

Results LAP was localized in 80.2% (n=81) cases and generalized in 19.8% (n=20) cases. In 60 cases (59.4%), lymph node sizes were found to be greater than 20×20 m...

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The Efficacy of Three Different Oral Hygiene Regimens in Preventing Chemotherapy-Induced Oral Mucositis in Pediatric Patients Receiving Hematopoietic Stem Cell Transplantation

Background Oral mucositis is one of the side effects developed post-hematopoietic stem cell transplant. This retrospective study aimed to assess the efficacy of a mouthwash mixture (lidocaine, sodium alginate, sucralfate, pheniramine) versus hyaluronic acid and a solution of sodium bicarbonate in terms of healing time and weight gain in the treatment of oral mucositis in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation with hemato-oncological malignancies.

Methods A ...

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Severe Lactic Acidosis, Wernicke’s Encephalopathy, and Wet Beriberi Due to Thiamine Deficiency in a Child With Leukemia

Thiamine (vitamin B1), which is a water-soluble vitamin, might lead to Wernicke’s encephalopathy (WE), wet beriberi, dry beriberi, and lactic acidosis when its serum concentration decreases (Polegato BF et al., Nutr Clin Pract 2019; 34: 558–564). WE is an acute syndrome that requires emergency treatment to prevent neurologic morbidity and death (Park SW et al., Korean J Pediatr 2014; 57: 496–499). It is rare in children and is characterized by the typical triad of ophthalmoplegia, ataxia, and co...

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The Clinical Journey of a Patient with Familial Mediterranean Fever: One Gene, Three Diseases

Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease characterized by recurrent self-limiting attacks of fever and serositis (Ben-Chetrit E and Levy M, Lancet 1998; 351: 659–664). The gain-of-function mutations in the responsible gene encoding pyrin, known as theMEditerranean FeVer (MEFV)gene, cause a reduction in the activation threshold of pyrin inflammasome triggering recurrent clinical attacks, subclinical inflammation, and a tendency for other inflammator...

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