A 67-year-old man was revealed a right upper lung nodule by accident during a chest CT examination 6 years ago, without any symptoms. The patient did not pay more attention to the pulmonary nodule and received no further treatment. Three years later, the patient presented with chest pain. A Chest contrast-enhanced CT showed a lobulated mass in the upper lobe of the right lung, with mild heterogeneous enhancement, and the upper edge of the mass locally invaded adjacent pleura. The patient underwent CT-guided needle biopsy, histopathological and immunohistochemical findings were consistent with diagnosis of pulmonary blastoma. Supplementary IHC of PD-L1(22C3) and PD-L1(E1L3N) were negative. In this case, we present the images of 18F-FDG PET/CT about a rare thoracic malignancy, pulmonary blastoma in adulthood, before and after chemotherapy and immunotherapy, which has never been reported before.

In this study, we present in detail a case of a thyroid nodule presenting with gastric neuroendocrine tumor (NET), which was incidentaly detected during a Gallium-68 (Ga-68) DOTATATE positron emission tomography/computed tomography (PET/CT) scan for staging and subsequently identified as papillary thyroid carcinoma on pathological examination. This rare case demonstrates that DOTATATE uptake can occur not only in NETs but also in thyroid cancers. This study emphasizes the importance of Fine Needle Aspiration Biopsy (FNA), especially in incidental thyroid nodules. It also highlights the place of Ga-68 DOTATATE PET/CT in clinical practice and the importance of further research in this field.

Die Autoren veröffentlichen eine Verfahrensanweisung zur szintigrafischen Lokalisation von Wächterlymphknoten beim malignen Melanom, beim Mammakarzinom, beim Penis- und Vulvakarzinom sowie bei Kopf-Hals-Tumoren und beim Prostatakarzinom. Wesentliche Ziele der szintigrafischen Wächterlymphknotendiagnostik bestehen in der Minimierung des Operationsausmaßes und der postoperativen Morbidität sowie der Optimierung der histopathologischen Aufarbeitung durch Fokussierung auf die relevanten Lymphknoten....

Aim To investigate the relationship between off-target binding of the amyloid tracer [¹⁸F]florbetaben (FBB) in the skull and skull density.

Methods Forty-three consecutive patients were included retrospectively (age 70.2±7.5y, 42% females, 65% amyloid-positive). For each patient, CT skull density (in Hounsfield units) and (late) FBB uptake in the skull were obtained using an individual skull mask generated by warping the skull tissue probability map provided by the statistical parametric mapping so...

Chimeric antigen receptor (CAR) T-cell therapy has dramatically shifted the landscape of treatment especially for Non-Hodgkin-Lymphoma (NHL). This study evaluates the role of fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT) in NHL treated with CAR T-cell therapy concerning response assessment and prognosis.

We evaluated 34 patients with NHL who received a CAR T-cell therapy between August 2019 and July 2022. All patients underwent a pre-therapeutic FDG-PET/CT (PE...

Aim The aim of this study is to investigate whether computer-aided, semi-automated 3D lung lobe quantification can support decision-making on PE diagnosis based on the ventilation-perfusion ratio in clinical practice.

Methods A study cohort of 100 patients (39 male, 61 female, age 64.8±15.8 years) underwent ventilation/perfusion single photon emission computed tomography (V/Q-SPECT/CT) to exclude acute PE on SPECT/CT OPTIMA NM/CT 640 (GE Healthcare). Two 3D lung lobe quantification software tools (...