Paragangliomas are rare neuroendocrine tumors arising from the chromaffin cells of the neural crest1. Their incidence is estimated to be less than 1 per 100000 people per year2. Paragangliomas can be distributed along sympathetic or parasympathetic chains from the base of the skull to the prostate, but the majority are located in the abdomen3. Cardiac paragangliomas are exceedingly rare, with less than 200 reported cases to date4. While paragangliomas are usually solitary, multiple paraganglioma...

Technetium-99m methoxyisobutyl isonitrile (Tc-99m MIBI) is widely used in myocardial perfusion scintigraphy (MPS) and parathyroid scintigraphy (PS). Tc-99m MIBI is also known to accumulate in malignant tissues, particularly in breast cancer. Here, we present a male patient who underwent MPS imaging and was subsequently diagnosed with breast cancer thanks to focal radiotracer uptake observed in the breast region. Additionally, we briefly discuss male breast cancer in the context of this case. To ...

The role of fibroblast activation protein inhibitor (FAPI) PET CT scan is not well documented in papillary thyroid cancer (PTC) patients. Patients with radioiodine refractory PTC and high thyroglobulin levels need PET/CT scan which is generally done by 18F FDG. In the current study, the diagnostic performance of 68Ga FAPI and FDG PET/CT scans were compared head to head in patients with radioiodine refractory PTC.

Fourteen patients with negative whole body Iodine scans and high thyroglobulin level...

To determine the value of radiomics data extraction from baseline 18F FDG PET/CT in the prediction of tumor-infiltrating lymphocytes (TILs) among patients with primary breast cancer (BC).

We retrospectively evaluated 74 patients who underwent baseline 18F FDG PET/CT scans for BC evaluation between October 2020 and April 2022. Radiomics data extraction resulted in a total of 131 radiomic features from primary tumors. TILs status was defined based on histological analyses of surgical specimens and ...

In this retrospective study, we evaluated the diagnostic value of [¹⁸F]FDG PET/CT in preoperative assessment of extrahepatic cholangiocarcinoma (ECC) and to develop a PET-based diagnostic algorithm for ECC.

Patients with suspected ECC with biliary obstruction were included. Patients received [¹⁸F]FDG PET/CT scan and image analysis. FDG uptake was semi-quantified using the SUV_maxof the suspected primary tumor, lymph nodes and metastatic lesions. Sex, age, tumor location, enhancement patterns and t...