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Nuklearmedizin

DOI 10.1055/s-00034924

Nuklearmedizin

In dieser Ausgabe:

Experimental 177 Lu-PSMA-617 radioligand therapy in a patient with extended metastasized leiomyosarcoma

Systemic radionuclide therapy with177Lu-PSMA-617 is a novel treatment option in patients with metastasized and castration-resistant prostate cancer4. The molecular target of the177Lu-PSMA-617 radioligand therapy is the prostate-specific membrane antigen (PSMA) highly expressed on prostate cancer cells. Beyond the enhanced accumulation of PSMA on prostate cancer cells, PSMA expression is also found on the molecular surface or in the tumor-associated neovasculature of various tumor tissues includ...

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Application of 99m Tc-UBI 29–41 scintigraphy in knee periprosthetic infection diagnosis

Aim  In recent years, the use of total knee arthroplasty (TKA) is considered a safe and cost-effective orthopedic procedure for alleviating the chronic pain and treatment of progressive osteoarthritis. This procedure may have some complications including periprosthetic infection as the most serious and aseptic loosening as the most common one. Differentiating between these entities is important because each has a different therapeutic approach. This study was conducted to investigate the ability ...

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