New Science of Synthesis Reference Library Volume Introduces the Most Advanced Methods in Organoboron Chemistry

Stuttgart, December 2019 – Science of Synthesis 4.16, the latest release of Thieme’s definitive reference resource on reliable synthetic methods, now provides the international chemistry community with a collection of the most useful, practical and up-to-date methods for boron activation and boron reactivity. Additionally, the new release features updates on various aromatic and partially saturated heterocyclic systems, O,N- and S,S-acetals, chloro-, bromo- and iodoalkenes, as well as the metal-catalyzed synthesis of peroxides. Direct links to Thieme Chemistry’s discovery tool SynOne facilitate an even broader search.

The latest addition to the Science of Synthesis Reference Library, “Advances in Organoboron Chemistry towards Organic Synthesis”, edited by E. Fernández, covers key concepts of organoboron chemistry and includes experimental procedures as well as the most advanced solutions for challenging transformations. Pioneers and leaders in the field describe practical and conceptual aspects of the rapidly growing field of organoboron chemistry. Experts as well as newcomers to the area are thereby provided with a collection of instantly applicable, reliable tools for the synthesis and use of organoboron compounds, most of them reported within the last decade. In this way, the rich chemical potential of organoboron compounds can be exploited.

The SOS Reference Library comprises volumes covering special topics in organic chemistry. With expert-evaluated content focusing on subjects of particular current interest, the SOS Reference Library complements the SOS Knowledge Updates to make Science of Synthesis the complete information source for the modern synthetic chemist.


Updates on essential synthetic methods


The latest Knowledge Update for SOS 4.16 covers synthetic methods for the synthesis of diverse aromatic and (partially) saturated heterocyclic systems, which continue to play an important role in pharmaceutical and medicinal chemistry. Acknowledging the synthetic importance of halogenated compounds, not least in cross-coupling chemistry, SOS 4.16 includes an update on the synthesis of chloro-, bromo-, and iodoalkenes by P. Huy and C. Czekelius, presenting new and improved ways of producing these versatile compounds.

Another highlight of the latest SOS Knowledge Update is a review on the metal-catalyzed synthesis of peroxides by B. Gnanaprakasam and M. B. Chaudhari. Updates on the synthesis of O,N-acetals, provided by S. Minakata, K. Kiyokawa and Y. Takeda, and on the deprotection of S,S-acetals by K. Sugamata and T. Sasamori are included as well.

Science of Synthesis is continuously revised and expanded. High-quality content is guaranteed by using clearly defined criteria for method selection as well as established editorial processes. The Editorial Board, in conjunction with the volume editors and expert authors, reviews the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluates significant developments in synthetic methodology.


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