SYNLETT Call for Papers

Upcoming SYNLETT Clusters open for submissions are listed below!

General Guidelines

• If you intend to submit a manuscript, please inform the corresponding (guest) editor first, remembering to include the title of your manuscript and the article type (e.g. Account or Letter).
• Upon approval by the (guest) editor, you may submit your manuscript according to the author instructions.
• Please include the title of the Cluster and the corresponding editor during the submission process.

Upcoming Topics

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Biomimetic Synthesis
Ang Li (Send e-mail) / Yefeng Tang / Jun Deng
Deadline: December 31, 2022
Link to the virtual issue coming soon

Inspired or learning from nature is always a great approach to solve problems. In terms of organic synthesis, it is wise to imitate nature’s way to overcome difficulty in making complicated molecules. As a rapidly emerging research field, biomimetic synthesis has attracted increasing interest of organic chemists from methodologies to total synthesis in the past decades. Researchers working on biomimetic synthesis are highly welcome to contribute to this Special Cluster.

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Dispersion Effects 
Peter R. Scheiner / Stefan Grimme / Benjamin List (Send e-mail) 
Deadline: December 31, 2022
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Dispersion interactions are the counterpart of steric repulsion that has served classic models in organic synthesis well. Over the last few years is has become apparent that the interplay of the two is essential for understanding thermodynamic stability, molecular recognition, chemical selectivity through transition-state stabilization, protein folding, enzyme catalysis, and more. Dispersion is much better understood now but it is not yet at the verge of being routinely included in synthesis planning. Making rational use of dispersion as a strategic element in synthesis is therefore a timely issue. 

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Thieme Chemistry Journals Awardees 2022 
Stefanie Baumann (Send e-mail) / Susanne Haak / Benjamin List
Deadline: December 31, 2022

Link to the virtual issue coming soon

This Special Edition includes contributions from the 'Thieme Chemistry Journals Awardees 2022’ 

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Organic Chemistry Under Visible Light: Photolytic and Photocatalytic Organic Transformations
 Subhabrata Sen (Send e-mail) / Gremaud Ludovic
Deadline: May 31, 2023
Link to the virtual issue coming soon

Thermal energy has facilitated innumerable organic reactions for ages. Since the dawn of this century, the consciousness about environment preservation led to the investigation of various energy sources that can replace thermal energy to facilitate organic reactions. Subsequently, visible light has been utilized to promote organic transformations. Such reactions are performed in the presence or absence of catalysts, bases, and solvents to generate organic molecules under sustainable reaction conditions. This upcoming special issue is aimed at highlighting the development of photolytic, photocatalytic, and photoelectrochemical strategies that can be implemented for the synthesis of organic molecules. The protocols under a chemical modality addressing an improved synthesis of numerous organic molecules are also welcomed. 

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Special Issue to Celebrate the Centenary Year of Prof. Har Gobind Khorana
Anant R. Kapdi/ Yogesh Sanghvi (Send e-mail) 
Deadline: July 31, 2023
Link to the virtual issue coming soon

This special issue calls for submissions to commemorate Centenary Celebration of Nobel Laureate Prof. Har Gobind Khorana for his outstanding contributions in the field of nucleic acid chemistry. Overall, nucleos(t)ides and oligonucleotides have had an immeasurable impact on design and treatment of cancer and viral infections including recent pandemic. For this issue we welcome work on advances made around synthetic methodologies involving an uncatalyzed, metal-mediated, or photocatalytic pathway for the synthesis of both functional and bioactive nucleic acid analogs including prodrugs. Biological activity (antibiotic, anticancer or antiviral) performed on the derivatized nucleos(t)ides /oligonucleotides, applications of the derived molecules as diagnostic probes or sensors will also be considered as a part of the special issue. Late-stage strategies pertaining to these privileged scaffolds providing access to DNA-enabled-libraries (DELs) and assembly of nanomaterials are also encouraged. We sincerely hope that you would consider submitting your research in the special issue honoring late Prof. Khorana. 

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Chemical Synthesis and Catalysis in India
Benjamin List (Send e-mail) / Santanu Mukherjee / Debabrata Maiti
Deadline: closed

This Special Issue aims to highlight the state of the art and the development of Chemsical Synthesis and Catalysis in India. 

Link coming soon

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Development and Applications of Novel Ligands/Catalysts and Mechanistic Studies on Catalysis
Ang Li (Send e-mail) / Zhipeng Zhang / Baoguo Zhao
Deadline: closed
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Ligands/catalysts especially the chiral ones have played a crucial role in modern synthetic chemistry, which enable organic chemists to invent numerous new transformations with great control of chemo-, regio-, stereo-, and/or enantioselectivities. During the last decades, various ligands/catalysts have been developed, greatly enlarging the toolbox of chemists for organic synthesis. In this cluster entitled “Development and Applications of Novel Ligands/Catalysts and Mechanistic Studies on Catalysis”, we welcome research papers as well as reviews regarding development or application of novel ligands/catalysts. Researches on development and application of novel chiral catalysts including transition-metal catalysts and organocatalysts especially developed in recent years are particularly encouraged. The related mechanistic studies are also highly welcome since mechanistic investigations could provide a better understanding of the pathways and promote further development and applications of the reactions.

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Organic Chemistry in Thailand
Yasuhiro Uozumi (Send e-mail) / Sumrit Wacharasindhu
Deadline: closed

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During the last decades, Thailand has been recognized as one of the countries within the Southeast Asia region with the greatest enthusiasm for organic chemistry. In celebration, this Cluster will showcase a wide range of cutting-edge findings from organic synthetic chemists in Thailand. 

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Machine Learning and Artificial Intelligence in Chemical Synthesis and Catalysis
Benjamin List (Send e-mail) /
Connor W. Coley
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Machine learning (ML) and artificial intelligence (AI) are currently substantially growing in all areas of chemistry but a Cluster devoted to applications in chemical synthesis and catalysis, despite the particularly tremendous potential of ML and AI in these areas, has been missing. If you are an active researcher in this field we invite you to contribute. 

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Design and Chemical Synthesis of Antivirals
Benjamin List (Send e-mail) /
Dirk Trauner
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Antivirals have had a major positive impact on human health. We think that considering the current world situation it is timely to celebrate the contributions of chemical antivirals to our life on this planet.

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Organic Photoredox Catalysis in Synthesis – Honoring Prof. Shunichi Fukuzumi's 70th Birthday
David A. Nicewicz (Send e-mail) / Shunichi Fukuzumi
Deadline: closed
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It is with great pleasure that we mark the 70th birthday of Prof. Shunichi Fukuzumi with a dedicated SYNLETT Cluster on 'Organic Photoredox Catalysis '  – to celebrate the career of Prof. Shunichi Fukuzumi and his many contributions to organic photoredox catalysis.

The Thieme WebCheminar Organic Photoredox Catalysis in Synthesis took place on September 28th. Hans-Achim Wagenknecht (KIT, Germany) and Todd Hyster (Cornell University, USA) feat. their post-docs and PhDs presented their latest research results. The event was chaired by SYNLETT Editor Dave Nicewicz (UNC Chapel Hill, USA).  

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Mechanochemistry
Tomislav Rovis (Send e-mail) / Jeffrey Moore
Deadline: closed

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A Thieme WebCheminar on Mechanochemistry took place on April 13, chaired by Jeffrey Moore (USA). Speakers: James Mack (USA), Stephen Craig (USA), Robert Göstl (Germany) and their group members.

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Late-Stage Functionalization
Benjamin List (Send e-mail) /
Tobias Ritter
Deadline: closed
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The term late-stage functionalization (LSF) is now frequently used in methodology development to describe transformations on complex molecules. Such reactions include catalytic and non-catalytic reactions, C–H functionalizations, and functional group manipulations, with one or several desired products.

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12th EuCheMS Organic Division Young Investigator Workshop (YIW2020/2021)
Stefanie Baumann (Send e-mail) / Susanne Haak 
Deadline: closed
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This Special Section includes contributions from the participants of the 12th EuCheMS Organic Division Young Investigator Workshop.

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Nickel in Catalysis
Rubén Martin (Send e-mail) /
Gary Molander
Deadline: closed
Access issue part I
Access issue part II

Taking into consideration the exponential growth in 'modern nickel-catalyzed reactions' to rapidly build up molecular complexity from simple precursors via one- or two-electron manifolds, it became clear that a Cluster in SYNLETT would be appropriate to highlight the outstanding possibilities that this field might offer to the community. Indeed, 'modern nickel-catalyzed reactions' has emerged as an invaluable methodology with numerous applications, ranging from classical synthetic organic (organometallic) chemistry to photoredox catalysis or even biologically-oriented endeavors. Therefore, we have decided to undertake this task and invite you to contribute to our Cluster by reporting on your most exciting work from your laboratories.