SYNLETT Call for Papers

Upcoming SYNLETT Clusters open for submissions are listed below!

General Guidelines

• If you intend to submit a manuscript, please inform the corresponding (guest) editor first, remembering to include the title of your manuscript and the article type (e.g. Account or Letter).
• Upon approval by the (guest) editor, you may submit your manuscript according to the author instructions.
• Please include the title of the Cluster and the corresponding editor during the submission process.

Upcoming Topics

First-Row Transition-Metal Catalysis For Organic Synthesis
Wei Shu (Send e-mail)
Deadline: January 31, 2025
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Owing to their abundance and low toxicity, first-row transition metals have emerged as a new paradigm in catalysis for developing catalytic reactions. This has led to the discovery of novel transformations and the improvement of known transformations previously enabled by noble metals. In recent years, first-row transition-metal catalysis has garnered increasing attention from the community for enabling bond activation and formation processes. First-row transition-metal selective bond formation has evolved into a powerful tool for organic synthesis. This issue welcome work, including but not limited to first-row transition metal (Ti, V, Cr, Mn, Fe, Co, Ni, Cu,) catalysis enabling selective transformations, including selective bond cleavage and formation processes in organic chemistry.

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Small Molecules in Medicinal Chemistry
Monika Raj / Arindam Talukdar / Raj Kumar / Satyasheel Sharma (Send e-mail)
Deadline: December 31, 2024
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Small molecules of synthetic or natural origin, make up 90% of pharmaceutical drugs. These compounds, characterized by their small molecular weight, serve as therapeutics for various diseases including cancer, neurological disorders, diabetes, viral infections, etc. Additionally, they are used as diagnostics, chemical probes, and sensors. This versatility is due to their ability to target a wide range of biological molecules, such as proteins (enzymes, ion channels, receptors), RNA, DNA, and glycolipids, acting as inhibitors, activators, antagonists, agonists, allosteric binders, and sensors. Moreover, the structural optimization of small molecules allows medicinal chemists to fine-tune their pharmacokinetic (absorption, distribution, metabolism, and toxicity) and pharmacodynamic properties (drug-receptor binding). Recently, small molecules have been successfully integrated into new modalities such as PROTACs, LYTACs, ADCs, molecular glues, cell and gene therapy facilitators, further expanding their research potential. We invite submissions on advancements in the design, synthesis, or semi-synthetic modification of novel small molecules with therapeutic or diagnostic importance highlighting their structure-activity relationship (SAR). Additionally, we welcome submissions on developments in novel synthetic routes, improved synthesis methods, and scalable, cost-effective syntheses of biologically important small molecules currently in clinical trials or on the market.

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Emerging Trends in Organic Chemistry: A Focus on India
Vinod Tiwari (Send e-mail)
Deadline: December 31, 2024
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India is among the top five countries in research output for both basic and applied organic chemistry. This special issue aims to highlight emerging trends in the field of organic chemistry at Indian universities. This issue welcome work, including but not limited to Novel synthetic methodologies and catalytic transformations, Total synthesis of complex natural products, Organic electrochemistry, photochemistry, Carbohydrate chemistry, heterocyclic chemistry, Organometallic and organocatalytic chemistry.

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Special Issue dedicated to Prof. B. C. Ranu 
Debabrata Maiti (Send e-mail) / Sukalyan Bhadra
Deadline: August 31, 2024
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This special issue is dedicated to Professor B.C. Ranu on the occasion of his 75^th birthday. Professor Ranu completed his master's and PhD from universities in Kolkata, India before pursuing postdoctoral research at Virginia Tech from 1982-1985. He has been a faculty member at the Indian Association for the Cultivation of Science since 1985. He superannuated from regular position in 2013 and is currently continuing as INSA Honorary Scientist within the same department. Professor Ranu's distinguished career has been recognized through several prestigious fellowships from Indian academies and the Department of Science and Technology. He has received multiple awards for his contributions, including the N.S. Narasimhan Award, Chemical Research Society of India medals, the J.C. Bose fellowship, and the J.C. Ghosh Memorial award. This special issue honors Professor Ranu's outstanding achievements and dedication to organic chemistry research and education.