SYNTHESIS Call for Papers

Upcoming SYNTHESIS Special Topics open for submissions are listed below!

General Guidelines

• If you intend to submit a manuscript, please inform the corresponding (guest) editor first, remembering to include the title of your manuscript and the article type (e.g. Review, Short Review, or Original Paper).
• Upon approval by the (guest) editor, you may submit your manuscript according to the author instructions.
• Please include the title of the Special Topic and the corresponding editor during the submission process.

Upcoming Topics

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Synthetic Development of Key Intermediates and Active Pharmaceutical Ingredients (APIs)
Joydev K. Laha/ Jianrong Steve Zhou  (Send e-mail)
Deadline: February 28, 2023
Link to the virtual issue (coming soon)

This upcoming special issue is aimed at highlighting the synthesis of pharmaceuticals including new chemical entities (NCEs), a key or advanced intermediate of a drug, or an active pharmaceutical ingredient (API).  The chemistry describing the synthesis of pharmaceuticals using cheap reagents, a chemical or photoredox catalytic condition, reagentless condition, an electrochemical method, and organic reaction in/on water can be reported. Any contribution on pharmaceutical synthesis including development of a novel synthetic process, an improved synthesis, a scalable and cost-effective synthesis, and concise preparation of a complex pharmaceutical is a good match for this issue. Any synthetic methodology exemplifying the synthesis of a pharmaceutical is also welcome.

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Advances in Skeletal Editing and Rearrangement Reactions
Corinna Schindler (Send e-mail) / Mark Levin 
Deadline: December 31, 2022
Link to the virtual issue (coming soon)

This SYNTHESIS special topic is aimed at highlighting recent advances in transformations that modify the heavy-atom skeleton of organic compounds, especially those amenable to late-stage synthesis. Transformations agnostic of the underlying chemical modality (e.g. transition metal catalysis, photochemistry, reagent development, etc.) will be presented alongside one another to highlight the complementary approaches to this multifaceted problem. Colleagues working in the broad area of skeletal editing are invited to contribute.

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Electrochemical Organic Synthesis
Liu-Zhu Gong (Send e-mail) / Hai-Chao Xu
Deadline: December 16, 2022
Link to the virtual issue (coming soon)

Recent achievement of electrochemical organic synthesis attracts increasing attention in the community. By applying electrochemical methods, chemists disclose new synthesis which could not happen under traditional thermal conditions and make organic synthesis green and sustainable. This SYNTHESIS special topic is aimed to showcase established and novel trends on electrochemical organic synthesis.

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SYNTHESIS Special Issue dedicated to Prof. David A. Evans
Corinna Schindler (Send e-mail) / Mark Lautens (Send e-mail)
Deadline: December  31, 2022
Link to the virtual issue (coming soon)

This Special Issue of SYNTHESIS pays tribute to Professor David Evans. We hope that this Special Issue will show the broad and positive impact of his mentorship on our scientific community today by highlighting current research in the form of manuscripts and reviews. Professor David Evans has mentored scientists from all over the world and created an atmosphere of vibrant scientific and cultural exchange in his laboratory.

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C–H Bond Functionalization of Heterocycles
Anil Kumar / T. Punniyamurthy (Send e-mail)
Deadline: December 31, 2022
Link to the virtual issue (coming soon)

This upcoming special topic highlights the work of key contributors who have made important synthetic advancements in C–H bond functionalization methods that lead to diversification of heterocyclic compounds and are amenable for late-stage C–H bond functionalization of bioactive natural products and pharmaceuticals. Improved catalytic systems and site-selective C–H functionalization of heterocycles will also become an important part of this special topic. 

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Special Issue dedicated to Prof. Cristina Nevado, Recipient of the 2021 Dr. Margaret Faul Women in Chemistry Award 
Corinna Schindler (Send e-mail) / Margaret Faul / Alois Fürstner 
Deadline: November 30, 2022
Link to the virtual issue (coming soon)

In 2021, Prof. Cristina Nevado from the University of Zurich (Switzerland) has been chosen as the second recipient of the Dr. Margaret Faul Award for Women in Chemistry. It is with great pleasure that we mark this prize award with a dedicated SYNTHESIS Special Issue to celebrate the career of  Prof. Cristina Nevado and her many contributions to organic synthesis. 

Read more about the award

Read more about the Winner 2021

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Synthetic Advancements Enabled by Phosphorous Redox
Corinna Schindler (Send e-mail) / Valerie Schmidt
Deadline: November 30, 2022
Link to the virtual issue (coming soon)

This special issue is aimed at highlighting the broad synthetic advancements made possible using the versatile redox capabilities of phosphorous-containing compounds. Strategies using single-electron and two-electron transformations, overall redox-neutral pathways, and phosphorous compounds interacting with transition metals will be presented alongside each other.

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Bürgenstock 2022: Future Stars in Organic Chemistry
Corinna Schindler (Send e-mail) / Mark Lautens (Send e-mail)
Deadline Closed

This Special Section will include contributions from the JSP fellows of the Bürgenstock conference 2022.
Link to the virtual issue (coming soon)

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Aryne Chemistry in Synthesis
Hideki Yorimitsu (Send e-mail) / Suguru Yoshida
Deadline closed
Access issue

Remarkable advances in modern aryne chemistry have enabled the efficient synthesis of a wide variety of aromatic compounds through aryne intermediates of characteristic reactivity. This SYNTHESIS Special Topic about 'Aryne Chemistry in Synthesis' – a field attracting a broad range of researchers in various disciplines such as pharmaceutical sciences and material chemistry – presents exciting synthetic methods including new reactions and strategies for synthesizing diverse aromatic molecules through highly reactive arynes.

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Asymmetric C–H Functionalization
Liu-Zhu Gong (Send e-mail) / Shigeki Matsunaga / Gong Chen 
Deadline closed
Access issue

Asymmetric C–H functionalization received increasing attention from researchers in the past decade due to its significance in the construction of molecular complexity without the need to pre-activate. Distinguishing the reactivity among multiple C–H bonds in a single molecule presents very challenging issues in organic synthesis and requires rigorous reaction design. 

In addition to the virtual collection a Thieme WebCheminar took place on May 11, chaired by Liu-Zhu Gong and Gong Chen. Joanna Wencel-Delord, Shigeki Matsunaga, Nicolai Cramer, and Bing-Feng Shi presented their latest research results.

Watch stream