• SYNFORM Editors

    SYNFORM Editor Matteo Zanda (right) with Editorial Assistant Alison Sage (left)

     

SYNFORM

SYNFORM is available as part of the online editions of SYNTHESIS, SYNLETT and SYNFACTS via Thieme E-Journals. This supplementary feature is available free of charge and presents people, trends, and views in synthetic organic chemistry with direct links to all quoted original papers. 

Want to read more articles? In our SYNFORM Archive you find all published articles at a glance.

Mechanism of Rhodium-Catalyzed Acylnitrene Transfer Reactions

S. Chang and D. Kim give mechanistic insights on Rh-catalyzed acylnitrene transfer reactions.

Immunological Evaluation of Escherichia coli O1-Derived Oligosaccharide-Protein Conjugates

K. Toshima and D. Takahashi describe a way to develop an avian pathogenic Escherichia coli O1 vaccine.

Multi-site Programmable Functionalization of Alkenes

Wanbin Zhang reports on the multi-site alkene functionalization via controllable isomerization.

Interview with Daniele Leonori

This Editorial Board Focus presents Daniele Leonori (RWTH Aachen University, Germany).

Interview with Yang Yang

This Young Career Focus presents Yang Yang (University of California Santa Barbara, USA).

Studies on Non-Radical Reactions of Dual-Functional Rh Catalysts

K. Tanaka and Y. Nagashima report about the design, synthesis and visible-light-induced of non-radical reactions.

Ni-Catalysed Enantioselective Hydrosulfenation of Alkynes

Qing-Wei Zhang and Gang Lu use nickel catalysis in the hydrosulfenation of alkynes.

Interview with Akimitsu Narita

This Editorial Board Focus presents Akimitsu Narita (Okinawa Institute of Science and Technology Graduate University, Japan).

Coupling of Aryl Nosylates with Diethanolamine Boronates

Philipp Kohler describes the Suzuki–Miyaura coupling of aryl nosylates and diethanolamine boronates.

Interview with Christoph Nitsche

This Young Career Focus presents Christoph Nitsche (Australian National University, Australia).

Copper-Enabled Photo-Sulfonylation of Aryl Halides

Dan Lehnherr describes the photo-sulfonylation of aryl halides using alkylsulfinates.

Interview with Vibha Tandon

This Editorial Board Focus presents Vibha Tandon (Jawaharlal Nehru University, India).

Interview with Irene Izzo

This Editorial Board Focus presents Irene Izzo (Università degli Studi di Salerno, Italy).

Interview with Martin Banwell

This Editorial Board Focus presents Martin Banwell (Institute for Advanced and Applied Chemical Synthesis, P. R. of China).

Copper-Enabled Photo-Sulfonylation of Aryl Halides

Dan Lehnherr describes the photo-sulfonylation of aryl halides using alkylsulfinates.

Interview with Taek Seung Lee

This Editorial Board Focus presents Taek Seung Lee (Chungnam National University, South Korea).

Interview with Tharmalingam Punniyamurthy

This Editorial Board Focus presents Tharmalingam Punniyamurthy (Indian Institute of Technology Guwahati, India).

Interview with Manuel Nappi

This Young Career Focus presents Manuel Nappi (University of Santiago de Compostela, Spain).

Interview with Ognjen Miljanic

This Editorial Board Focus presents Ognjen Miljanic (University of Houston, USA).

Synthesis of Calix[4]arene Appended Glycodendrimers

Vinod K. Tiwari presents a ‘CuAAC’ Click approach to build calix[4]arene-cored (ga)lactosylated G1 and G2 glycodendrimers.

Photochemical Diversification of Strong C(sp3)–H Bonds

Lei Gong shows the use of allyl bromide and NaF in photochemical C–H functionalization reactions.

Interview with Can Zhu

This Young Career Focus presents Can Zhu (Fudan University, P. R. of China).

Generation and Utilization of Bare Trifluoromethyl Anion in Flow

Dong-Pyo Kim presents the use of bare trifluoromethyl anion in flow via rapid biphasic Mixing.

Electrochemical Cobalt-Catalyzed Aryl C–H Activation

Lutz Ackermann describes new cobalt-catalyzed aryl C–H activation reactions.

Dehydrogenative Imination of Low-Valent Sulfur Compounds

Siegfried Waldvogel reports on the scalable synthesis of sulfilimines, sulfinamidines, and sulfinimidate esters.

Total Synthesis of Lissodendoric Acid A

Neil Garg used stereospecific trapping of a strained cyclic allene in the synthesis of lissodendoric acid A.

A Catalytic Enantioselective Stereodivergent Aldol Reaction

Alan Healy reports on an enantioselective stereodivergent aldol reaction catalyzed by salens.

Stabilizing Organolithium Reagents with Organogel Delivery Vehicles

Peter O’Brien and David K. Smith describe a method to stabilize organolithium reagents.

Interview with Ahmad Masarwa

This Young Career Focus presents Ahmad Masarwa (The Hebrew University of Jerusalem, Israel).

Organic Reaction Mechanism Classification Using Machine Learning

Igor Larrosa and Jordi Burés describe the application of machine learning in understanding reaction mechanisms.

Interview with Makeda Tekle-Smith

This Young Career Focus presents Makeda Tekle-Smith (Columbia University, USA).

Single-Carbon Atom Transfer to α,β-Unsaturated Amides

Mamoru Tobisu achieves the formation of four chemical bonds a carbon center in a single step.

Photochemical Enantioselective α-Alkylation with Pyridinium Salts

Uttam Tambar reports on a photochemical enantioselective α-alkylation reaction.

meta-Substituted Arene Bioisosteres from [3.1.1]Propellane

Edward Anderson describes the synthesis of meta-substituted arene from [3.1.1]propellane via a BCHep.

Dual Activation Strategy to Achieve C−C Cleavage of Cyclobutanes

Zhi-Xiang Yu reports on the [4+2] Cycloaddition of yne-vinylcyclobutanones using Rh/Zn co-catalysis.

Interview with Jung Min Joo

This Editorial Board Focus presents Jung Min Joo (Kyung Hee University, South Korea).

Interview with the SYNLETT Best Paper Award Winners 2022

Todd Hyster gives further insights to his award-winning paper on lactam radical cyclizations using a photoenzyme.

Interview with Thierry Ollevier

This Editorial Board Focus presents Thierry Ollevier (Université Laval, Canada).

Interview with Mattia Silvi

This Young Career Focus presents Mattia Silvi (University of Nottingham, UK).

Fe-Catalyzed Intermolecular Amination of Benzylic C(sp3)–H Bonds

Buddhadeb Chattopadhyay describes the intermolecular C(sp3)–H amination and its applications.

Enantioselective Reductive Transformations of Secondary Amides

Pei-Qiang Huang presents reductive transformations of secondary amides using a multicatalysis protocol.

meta-Selective C–H Arylation of Phenols

Liam Ball used a regiodiversion of electrophilic aromatic substitution for the C–H arylation of phenols.

Interview with the SYNTHESIS Best Paper Award Winners 2022

Christoph Schneider gives further insights to his award-winning paper on the asymmetric synthesis of fused tetrahydroquinolines.

Ring Contraction of Metallacyclobutadiene

Haiping Xia and Yu-Mei Lin present a synthesis of metallacyclopropene from metallacyclobutadiene.

Synthesis of Peptide Carbocycles

Steven Bloom used a “Snip-and-Stich” approach to synthesize a large variety of peptide carbocycles.

Interview with Johanna Blacquiere

This Young Career Focus presents Johanna Blacquiere (Western University, Canada).

Single-Atom Catalysis to Synthesize Nitriles

Zehui Zhang describes the oxidative synthesis of nitriles via C–C bond cleavage.

A Concise Synthesis of Tetrodotoxin

Dirk Trauner and Bryan Matsuura present a synthesis of tetrodotoxin, a potent poison found in some fish.

Interview with Jaideep Saha

This Young Career Focus presents Jaideep Saha (Centre of Biomedical Research, India).

The Griess, Sandmeyer, and Pschorr Reactions

This Name Reaction Biography highlights the reactions named after Griess, Sandmeyer and Pschorr.

Synthesis of cis-Thiiranes

Won-jin Chung and Jun-Ho Choi show a diastereoselective access to epoxide congeners.

Interview with Tian-Sheng Mei

This Editorial Board Focus presents Tian-Sheng Mei (Shanghai Institute of Organic Chemistry, P. R. of China).

Interview with Oliver Dumele

This Young Career Focus presents Oliver Dumele (Humboldt Universität zu Berlin, Germany).

Pd-Catalyzed Synthesis of Azaheterocycles

Peng Wang presents the synthesis of azaheterocycles starting from unactivated alkenes.

Enantioselective Diborylation of 1‑Chloro-1-trifluoromethylalkenes

Qiuling Song describes the Cu-catalyzed sp2/sp3 diborylation of 1‑chloro-1-trifluoromethylalkenes.

Electron in a Cube

Midori Akiyama reports on the synthesis and characterization of perfluorocubane.

Remote C–H Bond Functionalization of Cyclic Amines

Weijie Chen provides a Graphical Review on developments in C–H bond functionalization of cyclic amines.

Versatile Synthons in the Synthesis of Heterocycles

Mark Mitton-Fry presents recent highlight on the use of aryl methyl ketones in heterocycles synthesis in a Graphical Review.

C–H Bond Functionalization of Amines

Daniel Seidel summarizes recent results on C–H bond functionalization of amines in form of a Graphical Review.

Interview with Laurence Harwood and Daniel Seidel

This Editorial Board Focus presents the views of Laurence Harwood and Daniel Seidel on the journal SynOpen.

Total Synthesis and Activity of Stemoamide-Type Alkaloids

Takaaki Sato describes the synthesis and anti-inflammatory activity of stemoamide-type alkaloids.

meta-C–H Arylation of Anisole Derivatives

M. Ángeles Fernández-Ibáñez shows the direct synthesis of meta-arylated anisoles by reversing the conventional site-selectivity.

Interview with Markus Kärkäs

This Young Career Focus presents Markus D. Kärkäs (KTH Royal Institute of Technology, Sweden).

Palladium-Catalyzed trans-Hydroalkoxylation

Jérôme Waser reports on the counterintuitive use of an aryl iodide additive in C–H bond forming reactions.

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