Highly Enantioselective Synthesis of 3,4-Dihydropyrans

Phosphine-catalyzed cyclization reactions are of enormous synthetic value, evidenced by ubiquitous presence of ring structures in natural products and bioactive molecules. Over the last few years, the group of Professor Yixin Lu at the National University of Singapore has been interested in developing novel and versatile organic catalysts that can be readily derived from amino acids. One of the main research efforts of his group is to devise powerful approaches to access chiral ring motifs, especially those structures that are not yet accessible via existing methods, and the dihydropyrans synthesized in the highlighed paper are important skeletons of biological significance.

Read here the full article for free Highly Enantioselective Synthesis of 3,4-Dihydropyrans

Download SYNFORM or read it online
Get Trial Access to the chemistry journals