Monofluoro Aryl Acetates via Copper Catalysis
Rylan Lundgren presents a copper-mediated synthesis of monofluoro aryl acetates.
Copper-Mediated Synthesis of Monofluoro Aryl Acetates via Decarboxylative Cross-Coupling: A. Fahandej-Sadi, R. J. Lundgren Synlett 2017, DOI: 10.1055/s-0036-1588516
Man-made, synthetic fluorinated molecules continue to play a prominent role as drugs, agrochemicals, materials and much more. Fluoro-aryl acetic acid derivatives are important building blocks in fluoroorganic chemistry and feature a range of interesting biological activities. Professor Rylan J. Lundgren from the University of Alberta (Edmonton, Canada) has recently reported a new approach the the synthesis of the title compounds.