New Approach to a Ubiquitinated Histone Mimic
Jiabin Li and Honggang Hu present the synthesis of a new ubiquitinated histone mimic.
Synthesis of a Ubiquitinated Histone Mimic Bearing a New Thioether Linkage: Q. He, Y. Qi, C. Liu, J. Li, H. Hu
Synlett 2017, 28, DOI: 10.1055/s-0036-1588744
Ubiquitin is a small (76 amino acids) protein that can be added to a protein in an important biological process called ubiquitination, which has a number of
Ubiquitinated histone mimic bearing a new thioether linkagevergrößern
Professor Hu said: “A new ubiquitinated histone mimic through thioether linkage was successfully synthesized and proved to be a good surrogate for natural ubiquitinated histone.”