Pharmaceutical Substances - Version 4.0

The version 4.0 of Pharmaceutical Substances was launched in June 2016. This major release features:

  • a new user interface
  • a new structure Editor that runs in any standard browser (no need to install plug-ins)
  • the option to upload Molfiles and CDX-files
  • searching of all APIs and screening basic information for each drug also when you are not logged in

 

Pharmaceutical Substances 4.0 also contains 20 new APIs and a total of 36,238 structures, 11,429 reactions and 2,626 active pharmaceutical ingredients.

New APIs

  • Favipiravir
  • Ombitasvir
  • Panobinostat
  • Paritaprevir
  • Vorapaxar
  • Lenvatinib
  • Sacubitril
  • Avibactam
  • Telavancin
  • Dalbavancin
  • Oritavancin
  • Delamanid
  • Finafloxacin
  • Isavuconazole
  • Brexpiprazole
  • Eluxadoline
  • Sonidegib
  • Flibanserin
  • Lumacaftor
  • Riociguat

 

Thanks to the great efforts of Thieme publishers Pharmaceutical Substances 4.0 is now online with a new interface! This release contains 20 new and recently approved NCEs (some with a new mechanism of action and/or structure), stands for progress in medicinal chemistry and reflects the current approval policy of FDA and EMA. It includes among others five antibiotics, three of which are glycopeptides, three antivirals for treatment of hepatitis C, three anticancers, the new tuberculosis drug Delamanid, as well as the first cardiovascular NEP-inhibitor Sacubitril, which is approved in combination with Valsartan. A milestone in the therapy of cystic fibrosis was enabled by combination of the CFTR corrector Lumacaftor with the CFTR-potentiator Ivacaftor.

Prof. Axel Kleemann, Author

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Contact

Thieme Chemistry Marketing Phone:+49-711-8931-771 Fax:+49-711-8931-777 E-Mail