C-1 Building Blocks in Organic Synthesis
Authoritative overview of a dynamic field, written by 54 experts. Quality contributions providing the most reliable methodologies. Including typical and general experimental procedures.
C-1 Building Blocks in Organic Synthesis reviews a wide variety of reactions by which one carbon atom is added to an organic molecule, forming a C–C Bond. In spite of the numerous classic reactions of this kind, there has been enormous progress in recent years, especially for those reactions involving catalytic methods. Introduction of substituted methyl groups is a major challenge and only very recently the first catalysts have been discovered that enable the introduction of fluoromethyl groups in aromatics.
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