Science of Synthesis Reference Library

Expert evaluated content focusing on subjects of particular current interest. The series highlights new angles and perspectives of importance in organic synthesis.

The Science of Synthesis Reference Library comprises volumes covering special topics of organic chemistry in a modular fashion, with six main classifications:

  1. classical
  2. advances
  3. transformations 
  4. applications 
  5. structures
  6. techniques

Volumes in the Science of Synthesis Reference Library focus on subjects of particular current interest with content that is evaluated by experts in their field. Science of Synthesis, including the Knowledge Updates and the Reference Library, is the complete information source for the modern synthetic chemist.

Base-Metal Catalysis Base-Metal Catalysis

Recent advances in catalytic methods based on earth-abundant metals are discussed.

Electrochemistry in Organic Synthesis Electrochemistry in Organic Synthesis

Electrosynthesis represents an increasingly viable platform for molecular synthesis; this volume presents the key concepts, strategies, and latest advances.

Click Chemistry Click Chemistry

This volume describes the most useful click transformations, and their applications in the chemical, biological, and materials sciences

Free Radicals Free Radicals: Fundamentals and Applications in Organic Synthesis

Radical chemistry is undergoing a renaissance, both in the selective generation of organic radicals and in their use in organic synthetic reactions.

Dual Catalysis in Organic Synthesis Dual Catalysis in Organic Synthesis

Dual catalysis has developed rapidly over the last decade, and these volumes highlight the application of synergistic and cooperative dual catalysis as a means of efficiently increasing molecular complexity.

Advances in Organoboron Chemistry towards Organic Ssynthesis Advances in Organoboron Chemistry towards Organic Synthesis

This SOS volume provides a collection of the most useful, practical, and reliable methods for advanced borylation reactions.

Photocatalysis in Organic Synthesis Photocatalysis in Organic Synthesis

Photocatalysis has developed rapidly over the last decade and this volume aims to provide the defining, current reference work for the field.

Science of Synthesis – Flow Chemistry in Organic Synthesis Flow Chemistry in Organic Synthesis

Flow chemistry is much more than the adaption of batch processes to flow systems. This volume shows the enabling power of continuous flow to access new reaction types and different chemistry space.

SOS Catalytic Reduction in Organic Synthesis Catalytic Reduction in Organic Synthesis

Catalytic reductions are among the most used synthetic transformations. These two volumes focus on recent developments in catalytic hydrogenation methodology.

Catalytic Oxidation in Organic Synthesis Catalytic Oxidation in Organic Synthesis

This SOS volume covers the evolution and emerging concepts in catalytic oxidation, with a focus on “green” processes.

N-Heterocyclic Carbenes in Catalytic Organic Synthesis N-Heterocyclic Carbenes in Catalytic Organic Synthesis

This two-volume set from SOS provides a user’s guide to NHC chemistry and catalysis, thus facilitating the introduction of NHCs to novices as well as providing a toolbox for more-advanced users.

Metal-Catalyzed Cyclization Reactions Metal-Catalyzed Cyclization Reactions

These two SOS volumes present the broad scope of metal-catalyzed reactions for the synthesis of cyclic compounds, from long-established methods to state-of-the-art approaches.

Applications of Domino Transformations in Organic Synthesis Applications of Domino Transformations in Organic Synthesis

These two SOS volumes highlight the current state of the art for the synthesis of complex products by domino processes.

Catalytic Transformations via C—H Activation Catalytic Transformations via C—H Activation

In the best traditions of Science of Synthesis, this reference library work presents the state of the art in C—H activation chemistry, as compiled by experts in the field.

Biocatalysis in Organic Synthesis Biocatalysis in Organic Synthesis

These Science of Synthesis volumes present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis.

C-1 Building Blocks in Organic Synthesis C-1 Building Blocks in Organic Synthesis

The two volumes of C-1 Building Blocks in Organic Synthesis provide a critical overview of synthetic organic reactions that add one carbon atom to a substrate.

Multicomponent Reactions Multicomponent Reactions

This two-volume reference work on Multicomponent Reactions has been designed to summarize critically the relevant synthetic processes in a dynamic field, which is of interest to chemists in both academia and industry.

Cross Coupling and Heck-Type Reactions Cross Coupling and Heck-Type Reactions

Metal-catalyzed cross-coupling reactions are of central importance in modern chemistry. In 2010 the Nobel Prize for Chemistry was awarded to chemists working in the field.

Asymmetric Organocatalysis Asymmetric Organocatalysis

Organocatalysis is a dynamic, young field that is rapidly gaining significance for economical and environmentally friendly organic synthesis, both in academia and in industry.

Water in Organic Synthesis Water in Organic Synthesis

Water is a beautiful solvent, and this volume helps not only to illustrate this, but it should also help in inspiring chemists worldwide to find new approaches and techniques for its application in organic synthesis.

Stereoselective Synthesis Stereoselective Synthesis

Over 120 expert authors present the best methods currently available for the preparation of nonracemic compounds. These methods may be stoichiometric or catalytic, and the latter may include metal, organic, or enzyme catalysis.

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