Water in Organic Synthesis
Comprehensive overview of a rapidly progressing field, compiled by 47 experts. Critical review of aqueous reactions, covering almost all types of organic reactions. Including special techniques with water and industrial applications. Emphasis on environmental aspects.
Water in Organic Synthesis is essential for the organic chemist in helping gain a thorough appreciation of the latest and most reliable available methods for using water in organic synthesis. It illustrates how water can often be a viable and green solvent in the laboratory and provides a detailed introduction to the subject: background information, evaluated methods, practical applications, industrial applications, special techniques, and an overview of the latest trends. The reference work also helps in inspiring chemists worldwide to find new approaches and techniques for the application of water in organic synthesis. (TOC/Abstracts/Volume Editor's Preface)
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Shu Kobayashi: "While most organic reactions have been carried out in organic solvents for a long time, negative aspects of organic solvents have come to the fore recently; many organic solvents are volatile, flammable, sometimes explosive, and have a damaging effect on human health or on the environment. Water is obviously the first choice of alternative solvent; water is clean, non-toxic, inexpensive, and the most environmentally benign. Water is really beautiful in nature, and indeed she chose water as a 'solvent'. Many elegant in vitro reactions are carried out in water in our bodies, mainly catalyzed by enzymes. Why should mankind not choose to use water in synthesis?"
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