•  

A Novel Approach to Diarylated Esters and Phosphonates

Palladium-Catalyzed Hydroarylation of Diazocarboxylates and Diazophosphonates: S. M. Golitsin, I. P. Beletskaya, I. D. Titanyuk
Synthesis 2019, DOI: 10.1055/s-0039-1690758

 

The group of Dr. Igor Titanyuk from Moscow State University (Russian Federation) has previously reported a palladium-catalyzed hydroarylation of diazoacetic ester. Continuing research on this methodology in the group has recently led to the expansion of its scope for the hydroarylation of α-diazocarboxylates or α-diazophosphonates, leading to diarylated esters and phosphonates, respectively.

  •  

Dr. Titanyuk said: “Cross-coupling of diazo compounds with aryl iodides makes hardly accessible diarylated carboxylic acid and phosphonic acid derivatives available now!”

Get Trial Access to the chemistry journals
Download SYNFORM or read it online