The management of congenital lung malformations (CLM) remains controversial. The aim of this study was to analyze the timing, approach, and outcomes of surgical treatment in children with CLM.

A cohort study was conducted comparing children with CLM who underwent thoracoscopic resection with open resection via thoracotomy. All children were treated according to an institutionalized multidisciplinary coordinated treatment algorithm.

Between 2002 and 2019, 68 children with CLM were treated. Thoracos...

In 2018, we shortened the fasting time in our clinic for clear fluid to 1 h. Since 2021 ‘drinking until call to the operating theatre’ applies. This quality assurance study investigates whether this regulation has further shortened the fasting times and which factors influence its implementation.

In this prospective observational study, a two-part anonymous questionnaire from the attending anaesthetist and the parents was completed.

A total of 204 children were included in the study. The fasting t...

Ein männliches, eutrophes Frühgeborenes wurde nach vorzeitigem Blasensprung und unaufhaltsamer Wehentätigkeit in der 32+6 SSW mit 2160 g spontan geboren. Nach guter, postnataler Adaptation und problemlosem enteralen Nahrungsaufbau traten ab dem 3. Lebenstag wiederholt altblutige Magenreste auf, die bei klinisch stabilem Zustand und perzentilenkonformer Gewichtszunahme zunächst nicht weiter abgeklärt wurden. Unter dem Verdacht auf eine Late-Onset-Sepsis wurde eine antibiotische Therapie begonnen....

Mutations in theARFGEF2gene (ADP-ribosylation factor guanine nucleotide-exchange factor 2), a crucial regulator of intracellular vesicular trafficking, have been associated with multisystemic disorders. These include well-characterized neurodevelopmental abnormalities such as microcephaly, periventricular nodular heterotopia, refractory epilepsy, and dystonic movement disorders, as well as non-neurological features like restrictive cardiomyopathy (Sheen VL et al., Nat Genet 2004; 36: 69–76, Radh...