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T. Kurahashi and S. Matsubara show a new synthetic route to (trifluoromethyl)quinolines.

Xi-Sheng Wang describes the cobalt-catalyzed hydrocyanation of monofluoroalkenes.

Narihito Ogawa reports on the synthesis of (–)-heliannuol E by selective propargyl substitution.

Methods for the Synthesis and Modification of 1,4-Dioxanes Compiled and Reviewed for SOS

Nobel Prize in Chemistry 2021 has been awarded to Benjamin List and David MacMillan.

Prof. Martin Oestreich, TU Berlin (Germany), has joined the SYNFACTS team as editor for the category “Metals in Synthesis”.

From now on, Dr. Eduarda Silva, University of Porto (Portugal), takes care of Crowd Review for SynOpen.

Key Synthetic Routes to Piperazine Structures Comprehensively Reviewed for SOS

John Keating describes the Pd-catalyzed synthesis of pyrazolo[3,4-b]pyridine-3-carboxamides.

Yinan Zhang and Lihong Hu present an efficient route for the synthesis of (±)-epi-costunolide.

Put your knowledge of chemical names to the test!

New Science of Synthesis Review on Acyclic Geminal Bisperoxides

Anup Kumar Misra reports on the synthesis of an important pentasaccharide.

Jesper Kristensen describes an improved synthetic method for 25CN-NBOH.

The partnership aims at improving the prediction of chemical reaction results using artificial intelligence and synthesis data from Thieme's digital publication source for organic chemistry – Science of Synthesis.

If yes, now is your chance to become part of the Science of Synthesis Early Career Advisory Board and to be networking with internationally renowned chemists!

We are happy to announce the 1st Breaking Barriers Through Chemistry Conference on August 2nd-6th, 2021 - promoting collaboration with Mexican scientists from all areas of chemistry.

Professor Jean-Marc Campagne is welcomed to the team!

Boost your knowledge of modern spectroscopic methods! The textbook has been a standard reference for decades - now available in the 3rd edition.

Hokkaido University Researchers Review Borylative Ring Closure

Radical chemistry is undergoing a renaissance, both in the selective generation of organic radicals and in their use in organic synthetic reactions.

Josep Cornella reports on the introduction of tetra- and pentafluorosulfanyl groups into aryl compounds.

Eminent chemist and Science of Synthesis author Ei-ichi Negishi passed away on June 6th, 2021.

Professor Tim Donohoe joins the Science of Synthesis Editor Team.

Naoyuki Shimada describes the synthesis of various derived Weinreb amides.

Julian Garrec and Alexis Archambeau present the Pd-catalyzed synthesis of oxazocine scaffolds.

Recent developments in purine synthesis have been reviewed by Professor Stanislav Wnuk and colleagues.

Yukun Guan reports on the total synthesis of (+)-aphanorphine.

Raju Jannapu Reddy presents an efficient synthesis of allyl aryl sulfones.

Daniel Rampon describes the Ir(III)-catalyzed chalcogenylation of naphthalene derivatives.

James McNulty presents a catalytic, oxidative synthesis of olivetol and various derivatives.

Prof. Corinna Schindler, University of Michigan (USA), has joined the Editorial Board of SYNTHESIS.

Syntheses, patents and applications of drugs are accessible in an easy-to-use online version. Update 4.11 provides 26 new APIs.

Dr. Narendra Ambhaikar reviews recent synthetic routes to phenazine structures

Chen-Liang Deng describes the Ni-catalyzed intramolecular nucleophilic addition of aryl halides to aryl ketones.

Prof. Martin Oestreich, TU Berlin (Germany), joins the Editorial Board of SYNTHESIS.

Mohanad Shkoor synthesizes fluorenone-fused coumarins via DMPA catalysis.