• SYNFORM Editors

    SYNFORM Editor Matteo Zanda (right) with Editorial Assistant Alison Sage (left)



SYNFORM is available as part of the online editions of SYNTHESIS, SYNLETT and SYNFACTS via Thieme E-Journals. This supplementary feature is available free of charge and presents people, trends, and views in synthetic organic chemistry with direct links to all quoted original papers.

Want to read more articles? In our SYNFORM Archive you find all published articles at a glance.

Arthur Rudolph Hantzsch and the Synthesis of Nitrogen Heterocycles

This Name Reaction Biography sheds light on the role of Arthur R. Hantzsch in nitrogen heterocycles synthesis.

Nickel-Catalyzed Deaminative Cyanation

Mary Watson describes the Ni-catalyzed deaminative cyanation of alkyl amines.

Mechanochemical Transformation of Planar Polyarenes

Mihaiela Stuparu presents the synthesis of curved fused-ring structures.

Interview with Erin Stache

This Young Career Focus presents Erin Stache (Cornell University, USA).

Interview with Alberto Martinez-Cuezva

This Young Career Focus presents Alberto Martinez-Cuezva (Universidad de Murcia, Spain).

Catalytic Asymmetric Nucleophilic Fluorination

Xianxing Jiang describes trifluoroborate etherate as a useful fluorine source in asymmetric nucleophilic fluorinations.

Chemodivergent Manganese-Catalyzed C–H Activation

Lutz Ackermann and Marc Vendrell present the modular synthesis of fluorogenic probes.

Interview with Adelina Voutchkova-Kostal

This Young Career Focus presents Adelina Voutchkova-Kostal (George Washington University, USA).

C(sp3)–H Methylation

Shannon Stahl reports on the C(sp3)–H methylation using a transition-metal catalyst and a peroxide-based oxidant.

Photocatalytic C–H Activation

Patrick Walsh and Eric Schelter present new results on the photocatalytic C–H activation in small molecules.

A Minisci Approach to C–H Borylation of Azines

Daniele Leonori describes how C–H bonds in azines can be borylated using a Minisci approach.

Interview with Guillaume Berionni

This Young Career Focus presents Guillaume Berionni (University of Namur, Belgium).

Regioselective Activation of Benzocyclobutenones and Dienamides

Tao Xu reports on the creation of anti-Bredt bridged-ring systems by a [4+4] cycloaddition.

Illuminating the Dark Conformational Space of Macrocycles

Andrei Yudin describes a method for isolating unique and previously understudied conformations of macrocycles.

Interview with Stephen J. Butler

This Young Career Focus presents Stephen J. Butler (Loughborough University, UK).

1,2-Diamination of Unactivated Alkenes

Satoshi Minakata shows an iodine-catalyzed, diastereodivergent intermolecular 1,2-diamination reaction.

Benzylic C–H Acylation by Cooperative NHC and Photoredox Catalysis

Armido Studer reports on an application of cooperative NHC and photoredox catalysis.

Interview with Alexey Sukhorukov

This Young Career Focus presents Alexey Sukhorukov (N. D. Zelinsky Institute of Organic Chemistry, and D. Mendeleev University of Chemical Technology, Russian Federation).

C–F Bond Functionalizations of Trifluoroacetamides

Yi-Feng Wang and K. N. Houk describe C–F bond functionalizations via spin-center shifts.

Asymmetric Synthesis of α-Chiral Bicyclo[1.1.1]pentanes

Edward Anderson and Fernanda Duarte synthesized α-chiral bicyclo[1.1.1]pentanes.

Metal-Free Azidotrifluoromethylation of Unactivated Alkenes

Wen-Bo Liu presents trifluoromethanesulfonyl azide as a bifunctional reagent.

Asymmetric Three-Component Olefin Dicarbofunctionalization

Wen-Jing Xiao and Jia-Rong Chen describe a dual-catalyzed asymmetric olefin dicarbofunctionalization.

Solar and Visible Light Assisted Peptide Synthesis

Alex Szpilman and Yoav Eichen report on the assistance of light in the synthesis of peptides.

Interview with Quentin Michaudel

This Young Career Focus presents Quentin Michaudel (Texas A&M University, USA).

Interview with Martin Oestreich

This Editorial Board Focus presents Martin Oestreich (Technische Universität Berlin, Germany).

A Storable Feedstock for Preparation of [1.1.1]Propellane

Masanobu Uchiyama describes the α-cyclodextrin encapsulation of bicyclo[1.1.1]pentane derivatives.

Iron-Catalyzed Asymmetric Carboazidation of Styrenes

H. Bao and X. Zhang report on the Fe-catalyzed asymmetric carboazidation of styrenes including mechanistic studies.

Interview with Vittorio Pace

This Young Career Focus presents Vittorio Pace (University of Torino, Italy).

Interview with the SYNTHESIS Best Paper Award winners 2020

M. Kanai, K. Oisaki and K. Sakai talk about their award-winning paper on a new bond-weakening borinate catalyst.

Aleksei Yevgen’evich Chichibabin and Pyridine Chemistry

This Name Reaction Biography highlights the influence of Aleksei Y. Chichibabin on pyridine chemistry.

Synthesis of Arylamines and N-Heterocycles

Zhang-Jie Shi synthesizes arylamines and N-heterocycles by direct catalytic nitrogenation with N2.

Interview with the SYNLETT Best Paper Award winners 2020

P. Kraft, S. Riniker and Q. Wang tell the story behind their award-winning paper on a new family of rigid dienone musks.

[3+2] (Hetero)annulation of Nonconjugated Alkenes

Joint efforts of the groups of McAlpine, Liu and Engle lead to useful 2,3-dihydrobenzofurans, indolines, and indanes.

Access Chiral Azabicycles from Ammonium Ylides

Min Zhang and Yu Lan report on a Lewis acid catalyzed synthesis of chiral azybicycles.

Interview with Anat Milo

This Young Career Focus presents Anat Milo (Ben-Gurion University, Israel).

Mimicking Oxidative Radical Cyclizations of Lignan Biosynthesis

Jean-Philip Lumb gives insight to chemistry and biochemistry of Stage 3 DBCODs.

Converting Waste Polyethylene into Alkylaromatics

Susannah Scott describes new possibilities to use recycled carbon.

Interview with Michael Mastalerz

This Editorial Board Focus presents Michael Mastalerz (Ruprecht-Karls-Universität Heidelberg, Germany).

Total Synthesis and Structural Assignment of Cyclodepsipeptide Alveolaride C

Rajib Kumar Goswami presents the total synthesis of cyclodepsipeptide alveolaride C.

Nickel-Catalyzed Mono-Selective α-Arylation of Acetone

Abderrahmane Amgoune and Anis Tlili show the α-arylation of acetone with aryl chlorides and phenol derivatives.

Deuterated N-Alkyl Pharmaceuticals through Semiconductor Photoredox Catalysis

Chenliang Su describes the photoredox-catalyzed engineering of deuterated N-alkyl pharmaceuticals.

Interview with Debasis Banerjee

This Young Career Focus presents Debasis Banerjee (Indian Institute of Technology Roorkee, India).

Migratory Functionalization of Unactivated Alkyl Bromides

Chao Feng and Patrick Walsh describe the construction of all-carbon quaternary centers via transposed tert-C-radicals.

A Flexible Route to α-Diketones by Ozonolysis of Alkynes

George Kraus presents ozonolysis of alkynes as a convenient entry to α-diketones.

Diversity-Oriented Synthesis of Peptide-Boronic Acids

Christian Klein reports on the synthesis of peptide-boronic acids by a versatile building-block approach.

Interview with Miłosz Pawlicki

This Young Career Focus presents Miłosz Pawlicki (Jagiellonian University, Kraków, Poland).

Regio- and Enantioselective Allylic Alkylation of Terminal Alkynes

Changkun Li describes the Rh/Cu-catalyzed regio- and enantioselective synthesis of 1,4-enynes.

Asymmetric Remote C–H Borylation of Aliphatic Amides

Masaya Sawamura presents the Ir-catalyzed asymmetric C–H borylation of aliphatic amides and esters.

Boron-Enabled Geometric Isomerization of Alkenes

Ryan Gilmour uses selective energy-transfer catalysis for the isomerization of alkenes.

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