New Entry to Cyclopentyl Aryl Ketones via Lewis Acid Photoredox Catalysis
Tehshik Yoon presents a general protocol for radical anion [3+2] cycloaddition.
A General Protocol for Radical Anion [3+2] Cycloaddition Enabled by Tandem Lewis Acid Photoredox Catalysis: A. G. Amador, E. M. Sherbrook, Z. Lu, T. P. Yoon
Synthesis 2017, DOI: 10.1055/s-0036-1591500
Substituted and functionalized five-membered carbocylic rings are common in natural and bioactive compounds; however, their synthesis continues to present challenges in spite of the many methods existing for their preparation, for example cyclizations and ring expansions. Recently, Professor Tehshik P. Yoon and his group from the University of Wisconsin-Madison (USA) described a new, elegant approach to these compounds.