News-Archive 2018

Synthesis of 1-Alkylisoquinolines via Radical Cyclization 13.11.2018 Synthesis of 1-Alkylisoquinolines via Radical Cyclization

Liming Shao presents a metal-free synthesis of 1-alkylisoquinolines.

Biphenyls via Cross-Coupling of Arenediazonium Salts 13.11.2018 Biphenyls via Cross-Coupling of Arenediazonium Salts

Bernd Schmidt reports on the cross-coupling of arendiazonium salts via Pd catalysis.

Synthesis of Anthraquinones via Pd-Catalyzed Acylation 13.11.2018 Synthesis of Anthraquinones via Pd-Catalyzed Acylation

Gedu Satyanarayana describes a Pd-catalyzed acylation for the synthesis of anthraquinones.

Poster Prize awarded at JCS 08.11.2018 Poster Prize awarded at JCS

Jacqueline Pollini received a poster prize at the 9th Junges Chemie Symposium in Ruhr and receives an edition of Protecting Groups.

Dr. Leo Betschart 25.10.2018 Dr. Leo Betschart (ETH Zürich) Joins the SOS Advisory Board

Dr. Leo Betschart, Scientific Information Consultant in Chemistry at the ETH Zürich, has been appointed to the Advisory Board for Science of Synthesis.

Joseph Wang from the University of Oxford (UK) 16.10.2018 Poster Prize awarded at 22-ICOS

Joseph Wang received a poster prize at the 22-ICOS in Florence and receives a one-year subscription to SYNFACTS.

Synthesis and Applications of 4-Chloro-2-(trichloromethyl)pyrimidines 16.10.2018 Synthesis and Applications of 4-Chloro-2-(trichloromethyl)pyrimidines

Moisés Romero-Ortega reports on the synthesis and applications of various halogenated pyrimidines.

Catalyzed Conversion of Aldehydes into Nitriles 16.10.2018 Catalyzed Conversion of Aldehydes into Nitriles

Nicholas E. Leadbeater presents a combination of oxidation and photoredox catalysis to convert aldehydes into nitriles.

Tim Swager 01.10.2018 Tim Swager receives ACS Award

Tim Swager, Massachusetts Institute of Technology, receives the ACS Award 2019 in the field of polymer chemistry.

Juzeng An 25.09.2018 Poster Prize awarded at ECHC

Juzeng An received a poster prize at the ECHC 2018 in Lecce and receives a one-year subscription to SYNFACTS.

Marlen Externbrink 25.09.2018 Poster Prize awarded at ORCHEM

Marlen Externbrink received a poster prize at the ORCHEM 2018 in Berlin and receives a one-year subscription to SYNFACTS.

Margaret Faul 25.09.2018 Portrait of Dr. Margaret Faul

On the occasion of the first Women in Chemistry Award which will be awarded in 2019, we want to introduce Dr. Margaret Faul, after whom the award is named.

Flow Chemistry in Organic Synthesis 19.09.2018 Flow Chemistry in Organic Synthesis

This new Science of Synthesis volume shows the enabling power of continuous flow to access new reaction types and different chemistry space.

Thorsten Bach 30.08.2018 SYNTHESIS Editor Thorsten Bach receives Emil-Fischer-Medal

Prof. Thorsten Bach receives Emil-Fischer-Medal at ORCHEM in Berlin, September 10 - 12, 2018.

Synthesis of Aryl/Heteroaryl Amides via Nitriles Hydration 24.08.2018 Synthesis of Aryl/Heteroaryl Amides via Nitriles Hydration

Mitsuhiro Yoshimatsu reports on the synthesis of aryl and heteroaryl amides via nitriles hydration.

SynOpen 14.08.2018 Crowd review available at SynOpen

Submit your paper to SynOpen and try our novel crowd peer review process!

Stereospezifische Aminierung von Alkylboronsäureestern 14.08.2018 Stereospecific Amination of Alkylboronic Esters

James Morken describes the amination of primary, secondary, and tertiary alkylboronic esters.

Metathesis Reactions for Accessing β-Amino Acid Derivatives 14.08.2018 Metathesis Reactions for Accessing β-Amino Acid Derivatives

Loránd Kiss applies metathesis reactions in the synthesis and functionalization of β-amino acid derivatives.

Content 07.08.2018 Introducing Thieme's new discovery tool SynOne!

Researchers can find and compare relevant articles on organic synthesis in this new, free tool.

Poster Prize awarded at ICOMC 2018 02.08.2018 Poster Prize awarded at ICOMC 2018

Marc-Kevin Zaretzke received a poster prize at the 28th International Conference on Organometallic Chemistry and receives a one-year subscription to SYNFACTS.

Four young chemists win Poster Prizes at BOS 01.08.2018 Four aspiring young chemists win Poster Prizes at BOS 2018

Four chemists from the Baltic states were honored with SYNFACTS Poster Prizes at BOS 2018.

Dr. Philippa Cranwell, University of Reading (UK), joins the Editorial Board of the open access journal SynOpen. 01.08.2018 SynOpen welcomes a new editor!

Dr. Philippa Cranwell, University of Reading (UK), joins the Editorial Board of the open access journal SynOpen.

Poster Prize awarded at ISHC-21 25.07.2018 Natalie Hofmann receives poster prize

Hofmann received a poster prize and a one-year subscription to SYNFACTS at the 21st ISHC in Amsterdam.

LY Kieu Dung 28.06.2018 Poster Prize awarded at Applied Natural Products Symposium

LY Kieu Dung received a poster prize at the Applied Natural Products Symposium in Palaiseau and receives a one-year subscription to SYNFACTS.

Professor Cristina Nevado 05.07.2018 Professor Cristina Nevado joins Science of Synthesis Editorial Board

Prof. Cristina Nevado, University of Zürich´s Chemistry Institute, joins the Editorial Board of Science of Synthesis (SOS).

Selective Preparation of C2v-Symmetric Hexaphenylbenzenes 27.06.2018 Selective Preparation of C2v-Symmetric Hexaphenylbenzenes

Shuichi Hiraoka shows an entry to C2v-symmetric hexaphenylbenzenes via Suzuki coupling.

Stereoselective Oxidation of Titanium(IV) Enolates with Oxygen 27.06.2018 Stereoselective Oxidation of Titanium(IV) Enolates with Oxygen

Fèlix Urpí reports on the stereoselective oxidation of Ti(IV) enolates with oxygen.

Ring-Closing Metathesis Entry to Dienamide Heterocycles 27.06.2018 Ring-Closing Metathesis Entry to Dienamide Heterocycles

Hideaki Wakamatsu and Yuichi Yoshimura present a ring-closing metathesis of ene-ynamides.

New Dipeptide Organocatalysts for Aldol Reactions 21.06.2018 New Dipeptide Organocatalysts for Aldol Reactions

Eusebio Juaristi describes new dipeptide organocatalysts for enantiodivergent aldol reactions.

Poster Prize awarded at FACS 2018 15.06.2018 FACS 2018: Poster prize awarded

The SYNFACTS Poster Prize at the 17th French-American Chemical Society Meeting, Orléans, was awarded to Marie-Aude Hiebel

A Biomimetic Synthesis of des-Hydroxy Paecilospirone 14.06.2018 A Biomimetic Synthesis of des-Hydroxy Paecilospirone

Thomas Pettus presents a biomimetic synthesis of des-hydroxy paecilospirone.

SOS Catalytic Reduction in Organic Synthesis 13.06.2018 Catalytic Reduction in Organic Synthesis

Catalytic reductions are among the most used synthetic transformations. These two volumes focus on recent developments in catalytic hydrogenation methodology.

Monitoring Solid-Phase Reactions with Thin-Layer Chromatography 13.06.2018 Monitoring Solid-Phase Reactions with Thin-Layer Chromatography

Cheng-Chung Wang reports on the analysis of solid-phase reactions with thin-layer chromatography.

Multi-Component Synthesis of N-Unsubstituted 1,2,3-Triazoles 07.06.2018 Multi-Component Synthesis of N-Unsubstituted 1,2,3-Triazoles

Qin-Pei Wu describes a mild multi-component synthesis of disubstituted 1H-1,2,3-Triazoles.

Shengming Ma präsentiert eine enantioselektive Methode zur Allenylierung von terminalen Alkynolen. 07.06.2018 Organocatalytic Enantioselective Synthesis of 1,3-Disubstituted Allenols

Shengming Ma presents an enantioselective allenylation of terminal alkynols.

Improved Synthesis of Guanine Quadruplex Ligand Phen-DC3 16.05.2018 Improved Synthesis of Guanine Quadruplex Ligand Phen-DC3

Anne Petitjean reports on an improved synthesis of guanine quadruplex ligand Phen-DC3.

C–H Alkylation of Heteroarenes with Alkyl Bromides 16.05.2018 C–H Alkylation of Heteroarenes with Alkyl Bromides

Rui Shang presents the C–H alkylation of heteroarenes with tertiary and secondary alkyl bromides.

Ruben Martin 09.05.2018 Rubén Martín receives Hirata Award

SYNLETT Editor Rubén Martín, Institute of Chemical Research of Catalonia (ICIQ), Spain, is the winner of the Hirata Award 2018.

Synthesis of Nepetoidin B 02.05.2018 Synthesis of Nepetoidin B

John Ralph describes a simple and short synthesis of the natural product nepetoidin B.

Synthese von 2-Azabicyclo[n.2.0]alkan-abgeleiteten Bausteinen 02.05.2018 Synthesis of 2-Azabicyclo[n.2.0]alkane-Derived Building Blocks

Oleksandr Grygorenko presents the synthesis of 2-azabicyclo[n.2.0]alkane-derived building blocks.

Novel Approach to Organo-Phosphinates and Phosphonates 18.04.2018 Novel Approach to Organo-Phosphinates and Phosphonates

Koen Binnemans describes a new one-pot synthesis to access organo-phosphinates and -phosphonates more easily than in the past.

Conceptually New Approach to Ellipticine and the Oxoaporphine Core 29.03.2018 Conceptually New Approach to Ellipticine and the Oxoaporphine Core

Tibor Soós shows a regioexhaustive functionalization of the carbocyclic core of isoquinoline.

Difluoro(phenylsulfanyl)methane as a Formylating Agent 29.03.2018 Difluoro(phenylsulfanyl)methane as a Formylating Agent

Chutima Kuhakarn describes the electrophilic aromatic formylation with difluoro(phenylsulfanyl)methane.

Synthese eines 68Gallium-Komplexierungs-Wirkstoffs 28.03.2018 Synthesis of a Gallium Complexing Agent used in PET Tracers

Ata Makarem presents the synthesis of a PET tracer based on a Ga nuclide.

Erhöhte Tetrazin-Reaktivität in der IEDDA Reaction 22.03.2018 Increasing Tetrazine Reactivity in the IEDDA Reaction

Hannes Mikula shows that the N-acylation of 3-aminotetrazines leads to increased reactivity in bioorthogonal ligations.

Jiaan Shao and Wenteng Chen present the synthesis of polysubstituted 2-aminopyrroles. 20.03.2018 Multicomponent Entry to Polysubstituted 2-Aminopyrroles

Jiaan Shao and Wenteng Chen present the synthesis of polysubstituted 2-aminopyrroles.

Shigeki Matsunaga presents the Pd-catalyzed germylation of aryl bromides and aryl triflates. 09.03.2018 Palladium-Catalyzed Synthesis of Arylgermanium Compounds

Shigeki Matsunaga presents the Pd-catalyzed germylation of aryl bromides and aryl triflates.

Zhen Chen describes the synthesis of 1-monosubstituted 1,2,3-triazoles from propargyl alcohol. 09.03.2018 Synthesis of 1-Monosubstituted 1,2,3-Triazoles

Zhen Chen describes the synthesis of 1-monosubstituted 1,2,3-triazoles from propargyl alcohol.

Prof. Shu-Li You – Neuer Herausgeber bei Science of Synthesis 22.02.2018 Prof. Shuli You Joins Science of Synthesis Editorial Board

Prof. You, Director of the State Key Laboratory of Organometallic Chemistry at the Shanghai Institute of Organic Chemistry, China joined the board in January 2018.

Maurizio Benaglia beschreibt die Synthese von chiralen 1,2-Diaminoderivaten unter kontinuierlichem Fluss. 19.02.2018 Continuous-Flow Synthesis of Chiral 1,2-Diamino Derivatives

Maurizio Benaglia describes the synthesis of chiral 1,2-diamino derivatives under continuous flow.

Heinz Langhals presents a new way to synthesize azulene. 19.02.2018 New Synthesis of Azulene

Heinz Langhals presents a new way to synthesize azulene.

12.02.2018 SYNTHESIS/SYNLETT Best Paper Award Winners Announced

Congratulations to Tõnis Kanger, Masakazu Nambo and Cathleen Crudden for winning the Best Paper Awards 2017!

Christoph Hirschhäuser describes a new route for the synthesis of the S,S-DICHED catalyst. 07.02.2018 A Practical Synthesis of the S,S-DICHED Catalyst

Christoph Hirschhäuser describes a new route for the synthesis of the S,S-DICHED catalyst.

Neuartige Oxazolhaltige Aminosäuren 07.02.2018 Novel Oxazole-Containing Amino Acids

Adel Nefzi presents the synthesis and use of novel oxazolyl amino acids.

B-Ring-Kontraktion in Steroiden mittels Benzilsäure-Umlagerung 07.02.2018 B-Ring Contraction in Steroids via Benzilic Acid Rearrangement

Philipp Heretsch provides access to a rare sub-class of steroids via benzilic acid rearrangement.

Daniele Leonori berichtet über eine praktische Photoredox-Methode zur Synthese von Arylhydroxylaminen. 07.02.2018 Photoredox Synthesis of Arylhydroxylamines

Daniele Leonori reports on a practical photoredox method to synthesize arylhydroxylamines.

Mark Stradiotto describes the synthesis of unsymmetrical biheteroaryls via Ni-catalyzed Suzuki–Miyaura cross-couplings. 07.02.2018 Unsymmetrical Biheteroaryls via Suzuki–Miyaura Cross-Couplings

Mark Stradiotto describes the synthesis of unsymmetrical biheteroaryls via Ni-catalyzed Suzuki–Miyaura cross-couplings.

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