News-Archive 2019

15.10.2019 Mono- and Dihalogenation of 2-Aminopyrazine

Dolors Pujol presents an efficient method for the halogenation of 2-aminopyrazine.

08.10.2019 Novel Approach to Antihistamine-type Scaffolds

Gautam Panda describes the 1,6-aza-Michael addition of heterocyclic amines and amides to para-quinone methides.

Professor Jiang and Dr. Wang New Volume Editors for Volume 14 08.10.2019 Science of Synthesis Knowledge Updates – New Volume Editors

Professor Xuefeng Jiang and Dr. Ming Wang Appointed as Volume Editors for SOS Volume 14: Six-Membered Hetarenes with One Chalcogen

01.10.2019 Poster Prize awarded at ISySyCat 2019

Sbusisiwe Mbatha was awarded a poster prize at the 3rd International Symposium for Synthesis and Catalysis 2019 and receives a SOS Workbench Edition.

Professor Christoph Marschner 18.09.2019 Science of Synthesis Knowledge Updates – New Volume Editor

Professor Christoph Marschner appointed as Volume Editor for Volume 5: Compounds of Group 14 (Ge, Sn, Pb).

Four young chemists win Poster Prizes at BOS Ten aspiring young chemists win poster prizes at OMCOS 20

Ten talented young chemists received Thieme poster prizes at OMCOS 20.

M. Krasavin 06.09.2019 An Improved Synthesis of 2,5-Disubstituted Tetrazoles

Mikhail Krasavin shows the [3+2] cycloaddition of α-diazocarbonyl compounds with arenediazonium salts.

Sean Kerwin 06.09.2019 Total Synthesis of Shensongine A

Sean Kerwin describes the total synthesis of the pyrrole spiroketal alkaloid shensongine A.

P. Langer 30.08.2019 Synthesis of Novel Imidazothiadiazoles

Peter Langer presents a new protocol for the synthesis of fused imidazothiadiazoles.

Jawahar Jat 23.08.2019 Cu(II)-Catalyzed Beckmann Rearrangement of Ketones

Jawahar Jat and John Falck describe the Beckmann rearrangement of ketones using copper triflate as catalyst.

Esteban Mejía 23.08.2019 Allylic C–H Alkynylation via Copper Photocatalysis

Esteban Mejía achieved the synthesis of 1,4-enynes via Cu-photocatalyzed cross-dehydrogenative coupling.

Amol Atar 16.08.2019 Synthesis of Dumbbell-like Amine-Functionalized Bis-C60 Fullerene

Amol Balu Atar presents a photochemical synthesis of dumbbell-like functionalized bis-C60 fullerene.

29.06.2019 An Obituary for Dieter Enders

On June 29, 2019, the outstanding chemist and long-term SYNTHESIS Editor Dieter Enders passed away at the age of 73 in Aachen (Germany).

27.06.2019 It was not tricyanomethane, after all…

Klaus Banert corrects a misunderstanding refuting the supposed synthesis of tricyanomethane.

27.06.2019 Total Syntheses of (+)-Alexine and Related Alkaloids

Won-Hun Ham describes the total syntheses of (+)-alexine and related alkaloids.

Poster Prize awarded at Bioheterocycles 2019 26.06.2019 Poster Prize awarded at Bioheterocycles 2019

Soňa Krajčovičová was awarded a poster prize at the 18th International Conference on Heterocycles in Bioorganic Chemistry and receives a Biocatalysis Workbench Edition.

SOS Editorial Board Members 2019 21.06.2019 Science of Synthesis Editorial Board Meeting 2019

The SOS team was delighted to meet with their Editorial Board in San Sebastian, Spain to discuss new ideas regarding topics and trends in organic synthesis.

Photoredox Fischer Indole Synthesis 03.06.2019 Photoredox Fischer Indole Synthesis

Masato Kitamura and Jun Shimokawa present a mild photoredox version of the Fischer indole synthesis.

Synthesis of Resolvins and Derivatives 03.06.2019 Synthesis of Resolvins and Derivatives

Yuichi Kobayashi reports the synthesis of two resolvins and further derivatives.

Poster Prize awarded at Twente / Mainz Symposium 22.05.2019 Poster Prize awarded at Twente / Mainz Symposium

Four young chemists were honored with a Thieme poster prize at the Twente / Mainz Mini-Symposium.

Venkat Narsaiah presents the first total synthesis of a series of artekeiskeanols 13.05.2019 First Total Synthesis of Artekeiskeanol A, C and Altissimacoumarin D

Venkat Narsaiah presents the first total synthesis of a series of artekeiskeanols.

Iodoglycosylation and Iodocarboxylation of Glycals 13.05.2019 Iodoglycosylation and Iodocarboxylation of Glycals

Jie Yu uses Brønsted acids of Co(III) complexes for the iodoglycosylation of glycals.

Gold(III)-Catalyzed Synthesis of N,N-Aryl,Benzyl-amines in Water 10.05.2019 Gold(III)-Catalyzed Synthesis of N,N-Aryl,Benzyl-amines in Water

Hidemasa Hikawa and Isao Azumaya describe the dehydrative N-benzylation of electron-deficient anilines.

10.05.2019 Synthesis of Fatty Acid Intermediates via Hudrlik–Peterson Reaction

Yuichi Kobayashi reports on the application of the Hudrlik–Peterson Reaction for fatty acid intermediates.

Recyclable Graphene Oxide Nanosheet Supported Catalyst 17.04.2019 Recyclable Graphene Oxide Nanosheet Supported Catalyst

Myung-Jong Jin and Sang Eun Shim describe a recyclable Suzuki coupling catalyst.

A Stereoselective Synthesis of the ACE Inhibitor Trandolapril 17.04.2019 A Stereoselective Synthesis of the ACE Inhibitor Trandolapril

Hans-Günther Schmalz presents a stereoselective synthesis of trandolapril.

Photocatalysis in Organic Synthesis 10.04.2019 Photocatalysis in Organic Synthesis

Photocatalysis has developed rapidly over the last decade and this volume aims to provide the defining, current reference work for the field.

Prof. M. Krasavin 01.04.2019 New Entry to 3-Arylglutaconic Acid Derivatives

Mikhail Krasavin describes a new flexible synthesis of 3-arylglutaconic acid derivatives via Heck–Matsuda arylation.

Team 27.03.2019 Electrochemical C(sp³)–H Fluorination

Phil Baran reports on a new electrochemical C(sp³)–H fluorination method.

Teaserbild_L 27.03.2019 Asymmetric Synthesis of α-Hydrazino Ketones

Akira Yanagisawa presents the tin-catalyzed asymmetric α-amination of alkenoate cyclic esters.

CFZ_Autorenbild_L 27.03.2019 Synthesis of (–)-Boschnialactone and γ-Lycorane

Alejandro Cordero-Vargas shows the protecting-group-free synthesis of two natural products using a free-radical reaction.

Synthesis of the ABC-Ring System of Various Alkaloids 26.02.2019 Synthesis of the ABC-Ring System of Various Alkaloids

Teodoro Kaufman reports on the application of an olefin hydroacylation/Pomeranz–Fritsch cyclization.

Regioselective Halogenation of Coumarins 25.02.2019 Regioselective Halogenation of Coumarins

Min Zhang describes the copper-catalyzed regioselective halogenation of coumarins.

Synthesis of 4-(Arylmethyl)proline Derivatives 25.02.2019 Synthesis of 4-(Arylmethyl)proline Derivatives

Helma Wennemers shows the synthesis of 4-(arylmethyl)proline derivatives.

50 Years SYNTHESIS and 30 Years SYNLETT Anniversary 01.01.2019 Happy Birthday, SYNTHESIS und SYNLETT!

We celebrate the 50th birthday of SYNTHESIS and the 30th birthday of SYNLETT. Join us and enjoy over 80 articles by top chemists to honor the anniversaries!

Efficient Synthesis of a 5α-Reductase Inhibitor 19.02.2019 Efficient Synthesis of a 5α-Reductase Inhibitor

Shinya Harusawa presents the synthesis of 3-(tetrazol-5-yl)-3,5-pregnadien-20-one.

Epoxidation of a Cyclic Allyl-Amine by a Bifunctional Peracid 19.02.2019 Epoxidation of a Cyclic Allyl-Amine by a Bifunctional Peracid

Shuming Chen and Kendall N. Houk describe the origin of stereocontrol in epoxidation reactions.

Radiochemical Synthesis of 2-[18F]Fluorophenylalanine 12.02.2019 Radiochemical Synthesis of 2-[18F]Fluorophenylalanine

Bernd Neumaier presents a new radiochemical synthesis of a promising PET Tracer.

Asymmetric Mannich-Type Reaction of an α-Trifluoromethyl Amide 11.02.2019 Asymmetric Mannich-Type Reaction of an α-Trifluoromethyl Amide

Masakatsu Shibasaki describes the synthesis of isatin imines through asymmetric catalysis.

Chemoselective Aerobic Oxidation of Benzylic Alcohols 05.02.2019 Chemoselective Aerobic Oxidation of Benzylic Alcohols

Tsunehisa Hirashita uses aerobic conditions to oxidize primary benzylic alcohols chemoselectively.

One-Pot Reductive Conversion of Aldehydes into Acetic Esters 01.02.2019 One-Pot Reductive Conversion of Aldehydes into Acetic Esters

Marc Adler presents the conversion of aldehydes into acetic esters in one pot.

Visible-Light-Induced Adamantylation of Azoles 31.01.2019 Visible-Light-Induced Adamantylation of Azoles

Lutz Ackermann describes the visible-light-induced adamantylation of azoles.

PubChem 08.01.2019 Thieme Chemistry provides 700,000 structures to PubChem

The open database of PubChem is used by millions of users worldwide. Thousands of structures and links have been uploaded by Thieme Chemistry to the portal.

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