News-Archive 2021

13.09.2021 Genereller Zugang zu Pyrazolo[3,4-b]pyridin-3-carboxamiden

John Keating beschreibt die Pd-katalysierte Synthese von Pyrazolo[3,4-b]pyridin-3-carboxamiden.

26.08.2021 Seven-Step Synthesis of (±)-epi-Costunolide

Yinan Zhang and Lihong Hu present an efficient route for the synthesis of (±)-epi-costunolide.

12.08.2021 Another SOS Crossword is Now Available To Download

Put your knowledge of chemical names to the test!

12.08.2021 SOS Author Spotlight: Vera Vil’, Oleg Bityukov, and Alexander Terent’ev

New Science of Synthesis Review on Acyclic Geminal Bisperoxides

06.08.2021 Total Synthesis of a Microbiologically Important Pentasaccharide

Anup Kumar Misra reports on the synthesis of an important pentasaccharide.

05.08.2021 Synthesis of the Selective Serotonin 2A Receptor Agonist 25CN-NBOH

Jesper Kristensen describes an improved synthetic method for 25CN-NBOH.

Collaboration between IBM Research Europe and Science of Synthesis

The partnership aims at improving the prediction of chemical reaction results using artificial intelligence and synthesis data from Thieme's digital publication source for organic chemistry – Science of Synthesis.

27.07.2021 Science of Synthesis Knowledge Updates - New Volume Editor Appointed

Professor Jean-Marc Campagne is welcomed to the team!

09.07.2021 SOS Author Spotlight: Hajime Ito and Koji Kubota

Hokkaido University Researchers Review Borylative Ring Closure

Science of Synthesis Free Radicals: Fundamentals and Applications in Organic Synthesis 07.07.2021 Science of Synthesis Free Radicals: Fundamentals and Applications in Organic Synthesis

Radical chemistry is undergoing a renaissance, both in the selective generation of organic radicals and in their use in organic synthetic reactions.

25.06.2021 Synthesis of Ar-SF4Cl and Ar-SF5 Compounds from Arylphosphorothiolates

Josep Cornella reports on the introduction of tetra- and pentafluorosulfanyl groups into aryl compounds.

Professor Ei-ichi Negishi 24.06.2021 Thieme Chemistry mourns the loss of Prof. Ei-ichi Negishi

Eminent chemist and Science of Synthesis author Ei-ichi Negishi passed away on June 6th, 2021.

Professor Tim Donohoe 24.06.2021 Science of Synthesis Knowledge Updates – New Editor for Hetarene Content

Professor Tim Donohoe joins the Science of Synthesis Editor Team.

15.06.2021 Entry to N-Protected Serine/Threonine-Derived Weinreb Amides

Naoyuki Shimada describes the synthesis of various derived Weinreb amides.

15.06.2021 Oxa-(4+4)-Cycloaddition Entry to Oxazocine Scaffolds

Julian Garrec and Alexis Archambeau present the Pd-catalyzed synthesis of oxazocine scaffolds.

Professor Stanislav Wnuk — SOS Author for Chapter 16.17 28.05.2021 Science of Synthesis Update on Purines

Recent developments in purine synthesis have been reviewed by Professor Stanislav Wnuk and colleagues.

17.05.2021 Concise Total Synthesis of (+)-Aphanorphine

Yukun Guan reports on the total synthesis of (+)-aphanorphine.

04.05.2021 Synthesis of Allyl Aryl Sulfones from Morita–Baylis–Hillman Adducts and Thiosulfonates

Raju Jannapu Reddy presents an efficient synthesis of allyl aryl sulfones.

29.04.2021 Fe(III)-Catalyzed Synthesis of 1-Chalcogenylated Naphthalene Derivatives

Daniel Rampon describes the Ir(III)-catalyzed chalcogenylation of naphthalene derivatives.

29.04.2021 Catalytic Synthesis of Olivetol and Derivatives

James McNulty presents a catalytic, oxidative synthesis of olivetol and various derivatives.

29.04.2021 SYNTHESIS welcomes a new editor!

Prof. Corinna Schindler, University of Michigan (USA), has joined the Editorial Board of SYNTHESIS.

Dr. Narendra Ambhaikar 13.04.2021 Science of Synthesis Phenazines Update

Dr. Narendra Ambhaikar reviews recent synthetic routes to phenazine structures

06.04.2021 Nickel-Catalyzed Synthesis of Benzofuran Derivatives

Chen-Liang Deng describes the Ni-catalyzed intramolecular nucleophilic addition of aryl halides to aryl ketones.

23.03.2021 SYNTHESIS welcomes a new editor!

Prof. Martin Oestreich, TU Berlin (Germany), joins the Editorial Board of SYNTHESIS.

08.03.2021 Synthesis of Fluorenone-Fused Coumarins

Mohanad Shkoor synthesizes fluorenone-fused coumarins via DMPA catalysis.

08.03.2021 Stereoselective Synthesis of the Cotylenin A Aglycone Carbon Skeleton

Kazuyuki Sugita shows the stereoselective synthesis of the cotylenin A aglycone carbon skeleton.

08.03.2021 Novel Entry to Fluorinated Cyclopropanes

Elizabeth Jarvo reports on a new method to synthesize fluorinated cyclopropanes.

08.03.2021 Ni-H-Catalyzed Isomerization-Induced Cleavage of Allyl Ethers

A. Berkefeld and I. Fleischer present the Ni-H-catalyzed cleavage of allyl ethers.

08.03.2021 Continuous Photochemical Benzyne-Forming Process

Marcus Baumann describes the continuous photochemical synthesis of benzyne.

04.01.2021 An Obituary for Victor Snieckus

On December 18, 2020, the outstanding chemist and long-term SYNLETT and SYNFACTS Editor Victor Snieckus passed away at the age of 83.

02.02.2021 SYNTHESIS/SYNLETT Best Paper Award Winners 2020

M. Kanai and K. Oisaki for SYNTHESIS and P. Kraft, Q. Wang and S. Riniker for SYNLETT, together with their co-authors, are the recipients of the 2020 Best Paper Awards.

01.02.2021 Copper-Catalyzed Ring Expansion of Vinyl Aziridines

Jean-Marc Campagne and Renata Marcia de Figueiredo show the ring expansion of vinyl aziridines under mild conditions.

Professor Elena Fernández 01.02.2021 Science of Synthesis Knowledge Updates – New Volume Editor for volume 6.

Professor Elena Fernández is the new volume editor for Boron Compounds.

26.01.2021 Synthesis of Constrained Benzoxazepines and Imidazopyrazines

Taleb H. Al-Tel presents a modular approach to constrained benzoxazepine and imidazopyrazine systems.

26.01.2021 Synthesis of N-Aryl-1,2,3,4-tetrahydroisoquinolines

Franz Bracher describes a new, flexible route to N-aryl-1,2,3,4-tetrahydroisoquinolines.

26.01.2021 A Molecular Stereostructure Descriptor for Asymmetric Catalysis

X. Hong and S.-Q. Zhang developed a new SPMS descriptor for the featurization of van der Waals surface.

07.01.2021 A Catalytic One-Pot Synthesis of Indolyl Cyclobutanones

Francesco Secci presents a new synthetic method to construct indolyl cyclobutanones.

07.01.2021 Vitamin B12-Photo-Catalyzed Dicarbofunctionalization of Bromoalkenes

Dorota Gryko reports on the dicarbofunctionalization of bromoalkenes.

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