Prof. Koen Binnemans (KU Leuven, Belgium)zoom
Novel Approach to Organo-Phosphinates and Phosphonates
Selective Substitution of POCl3 with Organometallic Reagents: Synthesis of Phosphinates and Phosphonates: B. Verbelen, W. Dehaen, K. Binnemans
Synthesis 2018, DOI: 10.1055/s-0037-1609435
Organo-phosphinates and -phosphonates are useful compounds whose difficult synthesis – especially of the former – has limited their more widespread use in a number of areas, such as therapeutics, flame retardants and fine chemicals. Recently, the group of Professor Koen Binnemans from the KU Leuven (Belgium) has reported a convenient novel approach for these compounds from readily available starting materials.
One-pot synthesis of organo-phosphinates and -phosphonateszoom