Pharmaceutical Substances - Version 4.1

The version 4.1 of Pharmaceutical Substances was launched in October 2016.

Pharmaceutical Substances 4.1 contains 17 new APIs and a total of 37,131 structures, 11,574 reactions and 2,641 active pharmaceutical ingredients.


New APIs

  • Suvorexant
  • Fusidic Acid
  • Teicoplanin (update)
  • Cangrelor
  • Nilotinib (update)
  • Netupitant
  • Rolapitant
  • Tipiracil
  • Anidulafungin
  • Ospemifene
  • Alectinib
  • Lesinurad
  • Ixazomib Citrate
  • Cobimetinib
  • Selexipag
  • Apatinib
  • Osimertinib


“Anticancers are still the main focus of drug development. This is reflected also in the approval practice of FDA and EMA within the last 5 years with a relatively high share of new anticancer drugs. As a consequence, the new update with in total 17 monographs contains 7 recently approved anticancers, and 5 of them are protein kinase inhibitors.”

Prof. Axel Kleemann, Author

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