From left: L. Angelini, Dr. D. Leonori, J. Davies (University of Manchester, UK); M. A. Alkhalifah, Prof. N. S. Sheikh (King Faisal University, Saudi Arabia)zoom
Photoredox Synthesis of Arylhydroxylamines
Daniele Leonori reports on a practical photoredox method to synthesize arylhydroxylamines.
Photoredox Synthesis of Arylhydroxylamines from Carboxylic Acids and Nitrosoarenes: J. Davies, L. Angelini, M. A. Alkhalifah, L. Malet Sanz, N. S. Sheikh, D. Leonori
Synthesis 2018, 50, 821–830
Hydroxylamines are important compounds as they can be used as intermediates for a number of organic transformations; furthermore, the hydroxylamine function is widespread in biologically active molecules and natural compounds. However, the synthesis of hydroxylamines still represents a challenge for organic chemists. Recently, the group of Dr. Daniele Leonori from the University of Manchester (UK) reported a new and practical method for achieving the synthesis of the title compounds.
Photoredox synthesis of arylhydroxylamineszoom