Ring-Closing Metathesis Entry to Dienamide Heterocycles
Synthesis of Various Heterocycles Having a Dienamide Moiety by Ring-Closing Metathesis of Ene-ynamides: H. Wakamatsu, Y. Sasaki, M. Kawahata, K. Yamaguchi, Y. Yoshimura
Synthesis 2018, DOI: 10.1055/s-0037-1609857
New versatile synthetic methods for preparing a wide range of functionalized and variably-sized heterocycles continue to be in great demand by the organic chemistry community. In this context, nitrogen heterocycles are particularly valuable owing to their widespread presence in a number of bioactive and naturally occurring molecules. The group of Professor Yuichi Yoshimura and Dr. Hideaki Wakamatsu from Tohoku Medical and Pharmaceutical University (Japan) has recently described an interesting strategy for accessing six- to eight-membered heterocycles incorporating a dienamide function.
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