Sequential Suzuki Coupling entry to C2v-Symmetric Hexaphenylbenzenes

Selective Preparation of C2v-Symmetric Hexaphenylbenzene Derivatives through Sequential Suzuki Coupling: K. Ogata, T. Kojima, S. Hiraoka
Synlett 2018, DOI: 10.1055/s-0037-1610024


Hexaphenylbenzene is the core unit of novel organic materials and can be used for the synthesis of polycyclic aromatic hydrocarbons. Controlled and selective functionalization of the hexaphenylbenzene scaffold with different structural units is of interest for tailoring the properties of these organic materials. The group of Professor Shuichi Hiraoka from The University of Tokyo (Japan) has recently reported a new and versatile approach for the preparation of C2v-symmetric hexaphenylbenzene derivatives.

Professor Hiraoka said: “Combined with the selective alternate trilithiation reaction, our Suzuki cross-coupling conditions for low-reactive chlorinated hexaphenylbenzene derivatives will enable the preparation of a new library of potential hexaphenylbenzene derivatives.”
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