C–H Bond Functionalization of Amines: A Graphical Overview of Diverse Methods
Daniel Seidel summarizes recent results on C–H bond functionalization of amines in form of a Graphical Review.
Functionalization of sp3 C–H bonds in amines and their protected derivatives – such amides, carbamates, N-aryl amines, etc., which have great relevance as pharmaceuticals as well as structural scaffolds in natural products, besides finding crucial applications in materials science – can be accomplished through a number of synthetic methodologies.
This vibrant area of research was reviewed in 2021 by the first Graphical Review in SynOpen, authored by the group of Professor Daniel Seidel (University of Florida, Gainesville, USA), which covered the most important methods in this field, together with the related underlying mechanisms, while tracing the origin of each approach back to the original seminal report or literature precedent.
Read the full article C–H Bond Functionalization of Amines: A Graphical Overview of Diverse Methods
- PDF Chemistry Catalog 2022 (PDF, 4 MB)