Single-Carbon Atom Transfer to α,β-Unsaturated Amides from N-Heterocyclic Carbenes
Mamoru Tobisu achieves the formation of four chemical bonds a carbon center in a single step.
The issue of how to improve efficiency in increasing structural complexity of molecules is a major focus in organic chemistry. The group of Professor Mamoru Tobisu at Osaka University (Japan) has been working on the problem and the highlighted paper describes their recently developed method, which allows for the four chemical bonds to be formed at a carbon center in a single step, thereby shortening the chemical processes that are traditionally used in classical methods for constructing more elaborate structures.
Read the full article Single-Carbon Atom Transfer to α,β-Unsaturated Amides from N-Heterocyclic Carbenes