Synthesis of Arylamines and N-Heterocycles by Direct Catalytic Nitrogenation Using Dinitrogen
Zhang-Jie Shi synthesizes arylamines and N-heterocycles by direct catalytic nitrogenation with N2.
Owing to the significance of nitrogen-containing molecules, the incorporation of nitrogen atoms into organic molecules through C–N bond formation is a critically important process in organic chemistry. Due to environmental and economic reasons, it is becoming increasingly important to use more abundant, readily accessible, and economic nitrogen sources. According to Professor Zhang-Jie Shi from Fudan University (Shanghai, P. R. of China) “the ideal nitrogenation process – especially from the economic viewpoint – would involve direct use of dinitrogen (N2) as a nitrogen source to construct N-containing organic molecules, thus avoiding traditional processes based on platform chemicals such as ammonia or nitric acid.”
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